Professor Rik Thompson
Faculty of Health,
School of Biomedical Sciences
Biography
SPECIFIC FIELD OF EXPERTISE: Cancer Biology, Breast Cancer, Invasion and Metastasis, Epithelial Mesenchymal Transition, Matrix Metalloproteinases SHORT BIO: Prof Erik (Rik) Thompson studied extracellular matrix in the rat testis for his PhD and undertook postdoctoral training in breast cancer invasion and metastasis at NIH, USA and the Lombardi Cancer Research Center, Georgetown University Medical Center, USA. He established a breast cancer Invasion and Metastasis laboratory at Georgetown before returning to St. Vincent’s Institute, Melbourne in 1997 as Group Leader for Invasion and Metastasis in the Victorian Breast Cancer Research Consortium. In 2014, he joined IHBI QUT as Professor in Breast Cancer Research and Theme Leader for ‘Chronic Disease and Ageing’. In 2016, he took up the role of Associate Director of IHBI at the Translational Research Institute. This role was reclassified to Research Lead, QUT@TRI in February, 2021. Rik has worked in breast cancer for >30 years, focused primarily on invasion and metastasis, building on postgraduate training in extracellular matrix (ECM) and postdoctoral interests in matrix metalloproteinases (MMPs) and epithelial mesenchymal plasticity (EMP). EMP: Having reported EMP in highly invasive BC cell lines (Thompson, 1992), EMP has continued as a major research focus since returning to Australia in 1997, with funding from NHMRC, USDOD, Cancer Australia and NBCF. I created and led the NBCF-funded EMPathy Breast Cancer Program (2010-2016), which seeks to target EMP in BC diagnosis and therapy. EMPathy links 28 investigators across 20 Australian Institutions, seeking to exploit EMP for new diagnostic, prognostic and therapeutic opportunities in breast cancer, especially metastatic recurrence. EMPathy has a focus on EMP exhibited by circulating tumour cells (CTCs), as a window into the metastatic process and therapy resistance. Tissues before and after neoadjuvant chemotherapy have also been examined for EMP in relation to therapy resistance. We have characterised the PMC42 breast cancer model of mesenchymal-epithelial transition, and studied EMP in the MDA-MB-468 model in vitro and in vivo, with an emphasis on EGF, hypoxia, hybrid EMP phenotype and circulating tumour cells (CTCs). CTCs have been examined in breast and prostate cancer patient-derived xenograft models. Mammographic Density: A research focus on mammographic density (MD) as a hereditary risk factor for breast cancer was developed out of VBCRC collaborations with Prof John Hopper and Melissa Southey, based on a long standing interest in ECM. A vital interface was created between clinical collaborators including surgeons, radiologists and pathologists to confirm associations between MD and ECM through mastectomy accrual programs established initially in Melbourne and subsequently in Brisbane. We developed a novel ‘within woman’ comparison strategy for assessing high versus low MD, histologically, molecularly, in vitro and in vivo. Rik has also developed research interests in the pathobiology of mammographic density as a risk factor for breast cancer over the past decade. A model of pairwise comparison of high and low MD material was developed in terms of histological, biological and molecular analyses, both in vitro and in vivo. Rik is also active in advocacy around MD in Australia, as a founding member of the inforMD Alliance, and head of a working group of the Clinical Oncology Societies of Australia that developed a Facts and Issues Statement on MD for the COSA professional groups: https://www.cosa.org.au/media/332779/breast_density_facts_issues_final_approved_5march2021.pdf. Plasma Medicine: In collaboration with Prof Ken Ostrikov, QUT Professor and Plasma Medicine pioneer, and through co-supervision of Ms Peiyu (Freda) Wang, recent studies have shown that so-called triple negative breast cancer (TNBC) cell lines are selectively killed by plasma treatment, in association with mesenchymal phenotype and higher resting levels of reactive oxygen species. Other plasma projects include selective targeting of the SARS-Cov-2 (COVID-19) virus receptor ACE2. Personalised Cancer Medicine: The Centre for Personalised Analysis of Cancers (CPAC), a network of clinical-researcher partnerships in 12 tumour streams across Brisbane, was created with MRFF RART funding administered by BDHP. This initiative provides a foundation for the development of personalised ex vivo tumour models across multiple tumour streams as platforms to test response to standard of care and investigational therapies. The CPAC initiative includes several Brisbane Hospitals and Research Institutions, with clinician / researcher teams in many cases straddling multiple sites.Personal details
Positions
- Professor of Breast Cancer Research
Faculty of Health,
School of Biomedical Sciences
Keywords
Breast Cancer, Mammographic Density, Invasion and Metastasis, Matrix Metalloproteinases, Epithelial-Mesenchymal Transition, Extracellular Matrix, Transcriptomics
Research field
Medical biochemistry and metabolomics, Medical microbiology
Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2020
Qualifications
- PhD (Griffith University)
Professional memberships and associations
CURRENT APPOINTMENTS
02/2021- Research Lead, Queensland University of Technology, Brisbane, Australia, at the Translational Research Institute, Brisbane, Australia 07/2014 - Member, Translational Research Institute, Brisbane, Australia 04/2014 -
Professor of Breast Cancer Research, School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Australia PREVIOUS APPOINTMENTS
- 07/2016-01/2021 Associate Director, Institute of Health and Biomedical Innovation at the Translational Research Institute, Queensland University of Technology, Brisbane, Australia
- 04/2014- Honorary Professor, Department of Surgery, The University of Melbourne (tenured 14/10/2004)
- 04/2014- Adjunct Group Leader, Invasion and Metastasis Unit, St. Vincent's Institute of Medical Research, Melbourne, Australia
PROFESSIONAL MEMBERSHIPS:
- 2012 - Australian Genomic Technologies Association (AGTA) - Honorary Lifetime Member from 2012
- 2010- Clinical Oncology Societies of Australia
- 2009- Australia and New Zealand Breast Cancer Trials Group
- 2008-12 International Society for Matrix Biology
- 2005-10 British Association for Cancer Research
- 2000-12 International Protease Society
- 1996- Matrix Biology Society of Australia and New Zealand
- 1994- Australasian Microarry and Associated Technologies Association (AMATA); now the Australian Genomic Technologies Association (AGTA)
- 1993- The EMT International Association (TEMTIA)
- 1991- Australian Society for Medical Research
- 1990- Metastasis Research Society (International)
- 1986- American Association for Cancer Research (incl. Tumour Microenvironment Working Group)
- 1983- Australia & New Zealand Society for Cell Biology
Teaching
TEACHING POSITIONS:
2020 International Virtual Lecture Course on ‘Measuring and Modelling the Epithelial/Mesenchymal Plasticity Spectrum’. Co-Convenor and Participant. Webinar. (5 October 2020) 2019 LQB601 – Cancer Biology, Research Seminar; ‘Epithelial-mesenchymal plasticity in metastatic progression and therapy resistance in breast cancer’, QUT (20 August 2019) 2018 QUT Honours HLH107 – Mentorship in Science, Fri. Oct 26, 2018; Lecture LQB601 – Cancer Biology, Research Seminar; ‘Pathobiology of Mammographic Density (MD) for Improved Breast Cancer Prevention and Treatment’, QUT (5 Sept 2018) 2017 LQB601 - Cancer Biology, Research Seminar, "Unravelling the Pathobiology of Mammographic Density as a Breast Cancer Risk Factor", QUT (22 August 2017)
2016 LQB601 - Cancer Biology, Research Seminar, "Tumour Microenvironment & Epithelial Mesenchymal Plasticity in Human Breast Cancer", QUT (9 August 2016) 2015 LQB601 - Cancer Biology, Research Seminar, "Tumour microenvironment and metastasis"
2015-2017 Honours Seminar Assessment 2012, 2013 Casual Lecturer, EMT and stem cells (in CED830004 Stem cells in Development & Regeneration), The University of Melbourne 1995-1997 Facilitator, Problem Based Learning, Georgetown University Medical Centre 1992-1997 Assistant Professor, Histology Teaching, Dept. Anatomy and Cell Biology, Georgetown University Medical Center, Washington, DC, USA 1985 Casual Lecturer, School of Science, Griffith University, Brisbane, Australia 1980-1984 Casual Demonstrator and Teaching Fellow, School of Science, Griffith University, Brisbane
Experience
COMMUNITY ENGAGEMENT / LAY PITCHED ARTICLES
2021 Poster “Facts and Issues around Mammographic / Breast Density” at the Queensland Women’s Health Forum, 27 & 28 May 2021 at the Brisbane Convention Centre, South Brisbane, and the Princess Alexandra Hospital Symposium, August 24-27, 2011. Lloyd, Thomas; Thompson EW. The Conversation “COVID vaccine may lead to a harmless lump in your armpit, so women advised to delay mammograms for 6 weeks”, 23 April 2021. Lay article in “The Conversation”. https://theconversation.com/covid-vaccine-may-lead-to-a-harmless-lump-in-your-armpit-so-women-advised-to-delay-mammograms-for-6-weeks-159529. Follow up articles in The Financial Review (158,543 unique daily visitors; 7,577 average story audience). 27 April 2021 “COVID-19 vaccines may interfere with breast cancer screening” and radio interview with 2FER Radio (107.3) Sydney. 2019 Speaker at the Credit Union Australia (CUA) Pink Ribbon breakfast, Brisbane on 9 October 2019. $2,400 raised for NBCF. Speaker at the School of Biomedical Sciences at University of Queensland (UQ), St Lucia on 26 August 2019. “Epithelial Mesenchymal Plasticity Dynamics in Human Breast Cancer Model Systems”. Speaker at the Cancer Care Services Cancer Research Monthly Forum at Royal Brisbane Women’s Hospital (RBWH) on 28 May 2019. “Centre for Personalised Analysis of Cancers: A Brisbane-wide Collaborative Network for Therapeutic Analysis in Peri-Clinical Tumouroids” “Message from Associate Director IHBI” in the “What’s on at TRI” Weekly Update. Published March 2019 2018 Speaker at the Blush, Breast & Prostate Survivor Forum at St Andrew’s Hospital, Toowoomba on 20/10/18: ‘Mammographic Density and Breast Cancer Risk’ Research Blog: Metastatic Breast Cancer for Breast Cancer Trials Group. April 2018 https://www.breastcancertrials.org.au/research-blog?name=metastatic-breast-cancer
Speaker at the National Youth Science Forum on 16/1/18: Translational Research Institute. Introduction to Research areas (i) Mammographic Density and (ii) Epithelial Mesenchymal Plasticity.
2017 Mammographic Density Discussion Paper submitted to COSA Council on 28/7/17: COSA (Clinical Oncology Societies of Australia) is a peak body representing around 30 diverse cancer groups, and is in an excellent position to help bring a consensus view to the emerging issues around mammographic density. I have played a leadership role in bringing a Discussion paper forward to COSA, seeking support for a working group to engage the multiple stakeholder groups (Breast Cancer, Cancer Biology, Primary Care, Epidemiology, ANZ Breast Cancer Trails Group, Consumers, BreastScreen, Cancer Council Australia). Fully approved Discussion paper released March 2021. https://www.cosa.org.au/media/332779/breast_density_facts_issues_final_approved_5march2021.pdf
2016 Interviewed by Cosmos Magazine, published in “How breast cancer spreads before tumours can be detected” 16 December. https://cosmosmagazine.com/biology/how-breast-cancer-spreads-before-tumous-are-detectable
2016 Interviewed for Metastasis Research Society (MRS) News – ‘The Prognostic Value of Residual Disease in the “Cancer Free”.
2016 Speaker at the Choices Younger Women's Group at The Wesley Hospital Choices Cancer Support Centre on 5 April, 2016: “Epithelial Mesenchymal Plasticity, Circulating Tumour Cells and Mammographic Density”
2016 Founding member of inforMD (INformation FORum on Mammographic Density), an Australian alliance of breast cancer researchers who are aware of the importance of breast density in screening, diagnosis, and prevention of breast cancer, who want to start a conversation with the wider Australian community about breast density (www.informd.org.au). 2016 Active participant in National Media Campaign launched 4 October 2016 to raise awareness of mammographic density, to help inform women about this very important risk factor that in future, could improve mammographic screening and provide better breast cancer outcomes. Print/online media: Adelaide Advertiser “Cancers Missed in Dense Breasts”; Courier Mail Brisbane “Mammogram not enough: Researchers say Breast density is masking cancer”; Cairns Post, Cairns “Cancers Missed in Dense Breasts”; The Advertiser/Adelaide Now “Mammograms may not detect cancer in women with "denser" breast tissue: research”; Geelong Advertiser “Mammograms may not detect cancer in women with "denser" breast tissue: research”; mamamia.com.au “The important fact women aren’t being informed of during breast screenings”; Science Daily “Breast density matters in detection of breast cancer”;
2016 Britt K, Hugo HJ, Stone J, Hopper J, Dasari P, Thompson EW, Ingman, W. The Conversation “Women should be told about their breast density when they have a mammogram” October 4, 2016. Lay article in “The Conversation”. 2016
Thompson EW, Saunders CJ. “Men get breast cancer too”. May 3, 2016. Lay article in “The Conversation” published online in an online series entitled “Men’s hidden health conditions”. 2016 Radio 2HD Interview following up on The New Daily online article - How a blood test could detect breast cancer early; 16 March 2016 Interviewed – The New Daily – How a blood test could detect cancer early; published online 15 March 2016 Radio 2SER (Sydney) Early Morning Breakfast Interview - commenting on Monash University Melbourne findings – Why does stress help the spread of cancer? 7 March 2016 Radio 6PR (Perth) The Weekender with Darren De Mello - commenting on Monash University Melbourne findings – Why does stress help the spread of cancer? 6 March 2016 Host, Pink Ribbon – Blue Sky Breakfast – QUT & NBCF, Brisbane; 26 October 2015 Host, Pink Ribbon – Blue Sky Breakfast – QUT & NBCF, Brisbane; 9 October 2014 Host, Pink Ribbon Breakfast - NBCF, Brisbane; 21 October 2012 Speaker, King & Wood Malleson’s Pink Ribbon Breakfast, Melbourne; 19 October Speaker, Mother’s Day Classic, Melbourne; 13 May
- Speaker, King & Wood Malleson’s Pink Ribbon Breakfast, Melbourne; 21 October
Speaker, Blake Dawson’s Pink Ribbon Breakfast, Melbourne; 14 October Speaker, Annual General Meeting, Vermont Cancer Research Fundraising Group, Melbourne; 9 August ABC Melbourne Radio 774 (John Faine Show); 8 February The Age newspaper, Melbourne; 4 February
- ABC TV National News; Studies on extracellular matrix in correcting blindness; representing Bernard O’Brien Institute (BOBIM) and Melbourne University
ABC TV 7.30 Report; Studies on extracellular matrix in adipose tissue engineering; representing BOBIM and Melbourne University 2004 St. Vincent’s Hospital Medical Research Week, Melbourne; representing BOBIM, SVI, Melbourne Uni. Poster display and presentation and award committee member for the SVH Community
- Cancer Council Victoria Relay for Life, Melbourne; representing Cancer Council Victoria, St Vincent’s Institute for Medical Research (SVI) and Victorian Breast Cancer Research Consortium (VBCRC)
Australian Society for Medical Research Week, Melbourne, representing SVI, VBCRC; Poster display and interactive booth for the general public and school students.
EDITORIAL BOARDS/EDITOR FOR SCIENTIFIC JOURNALS:
- 2020 Guest Editor (with Mohit Kumar Jolly, Annapoorni Rangarajan, & Brett Hollier), SpringerLink, Special issue (Vol 100 No 3) of Journal of the Indian Institute of Science (J IISc).
- 2019 Associate Editor Cancer Immunity and Immunotherapy – Frontiers in ImmunologyCo-Guest Editor (with Pr. Guojun Sheng), Cells Tissues Organs Special Issue on the 9th International EMT Meeting, TEMTIA 2019
- 2015 - Co-Guest Editor (with Dr Don Newgreen), Cells Tissues Organs Special Issue on the 7th International EMT Meeting, TEMTIA 2015
- 2011- Editorial Board Member, Cancer Microenvironment
- 2011- Co-Guest Editor (with Dr. Don Newgreen, Dr. Carol La Bonne, Dr. Angels Fabra Fres), Cells Tissues Organs Special Issue on the 5th International EMT Meeting, TEMTIA 2011
- 2010- Co-Guest Editor (with Dr. Heide Ford), the Journal of Mammary Gland Biology Special Issue on Epithelial Mesenchymal Transition in Mammary Development and Cancer Principal Guest Editor, Cells Tissues Organs Issue ‘Epithelial Mesenchymal Transitions: New Advances in Development, Fibrosis and Cancer’ Co-Guest Editor (with Dr. Izhak Haviv), Cancer Microenvironment Special Issue on Microenvironment and Epithelial Mesenchymal Transition
- 2010- Associate Editor, Cells Tissues Organs
- 2008-10- Editorial Board Member, Cells Tissues Organs
- 2007-08- Guest Editor, Clinical Experimental Metastasis Special Issue on Epithelial Mesenchymal Transitions in Cancer, 25 (6), October 2008
- 2006-07- Guest Editor, Cells Tissues Organs Special Issue on the 2nd International EMT Conference, 2007
- 1995- Editorial Board Member, the Breast Journal Editorial Board Member, Clinical and Experimental Metastasis
Publications
- Hassan, S., Blick, T., Thompson, R. & Williams, E. (2021). Diversity of Epithelial-Mesenchymal Phenotypes in Circulating Tumour Cells from Prostate Cancer Patient-Derived Xenograft Models. Cancers, 13(11). https://eprints.qut.edu.au/209628
- Wang, P., Zhou, R., Thomas, P., Zhao, L., Zhou, R., Mandal, S., Jolly, M., Richard, D., Rehm, B., Ostrikov, K., Dai, X., Williams, E. & Thompson, E. (2021). Epithelial-to-Mesenchymal Transition Enhances Cancer Cell Sensitivity to Cytotoxic Effects of Cold Atmospheric Plasmas in Breast and Bladder Cancer Systems. Cancers, 13(12). https://eprints.qut.edu.au/211449
- Sheng, G., Thompson, E., Newgreen, D. & Denker, H. (2022). Twenty years on for The Epithelial-Mesenchymal Transition International Association (TEMTIA): an interview with co-founders Erik Thompson and Donald Newgreen. Cells Tissues Organs, 211(2), 252–260. https://eprints.qut.edu.au/211975
- Dai, X., Bazaka, K., Thompson, R. & Ostrikov, K. (2020). Cold atmospheric plasma: A promising controller of cancer cell states. Cancers, 12(11). https://eprints.qut.edu.au/205857
- Yang, J., Antin, P., Berx, G., Blanpain, C., Brabletz, T., Bronner, M., Campbell, K., Cano, A., Casanova, J., Christofori, G., Dedhar, S., Derynck, R., Ford, H., Fuxe, J., García de Herreros, A., Goodall, G., Hadjantonakis, A., Huang, R., Kalcheim, C., Kalluri, R., Kang, Y., Khew-Goodall, Y., Levine, H., Liu, J., Longmore, G., Mani, S., Massagué, J., Mayor, R., McClay, D., Mostov, K., Newgreen, D., Nieto, M., Puisieux, A., Runyan, R., Savagner, P., Stanger, B., Stemmler, M., Takahashi, Y., Takeichi, M., Theveneau, E., Thiery, J., Thompson, E., Weinberg, R., Williams, E., Xing, J., Zhou, B. & Sheng, G. (2020). Guidelines and definitions for research on epithelial-mesenchymal transition. Nature Reviews Molecular Cell Biology, 21(6), 341–352. https://eprints.qut.edu.au/202121
- Bhatia, S., Blick, T., Pinto, C., Waltham, M., Monkman, J., Ivanova, E., Pollock, P., Nagaraj, S., Wiegmans, A., Haviv, I., Simpson, K. & Thompson, E. (2020). Identifying therapies to combat epithelial mesenchymal plasticity-associated chemoresistance to conventional breast cancer therapies using an shRNA library screen. Cancers, 12(5). https://eprints.qut.edu.au/202254
- Williams, E., Gao, D., Redfern, A. & Thompson, R. (2019). Controversies around epithelial-mesenchymal plasticity in cancer metastasis. Nature Reviews Cancer, 19(12), 716–732. https://eprints.qut.edu.au/134078
- Bhatia, S., Monkman, J., Blick, T., Duijf, P., Hiriyur Nagaraj, S. & Thompson, R. (2019). Multi-omics characterization of the spontaneous mesenchymal-epithelial transition in the PMC42 breast cancer cell lines. Journal of Clinical Medicine, 8(8), 1–31. https://eprints.qut.edu.au/132820
- Redfern, A., Spalding, L. & Thompson, R. (2018). The Kraken Wakes: induced EMT as a driver of tumour aggression and poor outcome. Clinical and Experimental Metastasis, 35(4), 285–308. https://eprints.qut.edu.au/120711
- Thompson, E. & Hiriyur Nagaraj, S. (2018). Transition states that allow cancer to spread. Nature, 556(7702), 442–444.
QUT ePrints
For more publications by Rik, explore their research in QUT ePrints (our digital repository).
Awards
- Type
- Appointment to Prestigious Positions
- Reference year
- 2017
- Details
- 2017. Board Director, ANZBCTG (2017-2020). 2015 onwards. COSA Council Member. COSA is the peak national body representing health professionals from all disciplines whose work involves the care of cancer patients. Our vision is "quality multidisciplinary cancer care for all". 2015-2017. TEMTIA Management Committee member (ex-officio, immediate past President. 2015 onwards. Member, Outreach I Working Group, Metastasis Research Society (International). 2014 onwards. Honorary Lifetime Member, Australasian Genomics Technologies Association
- Type
- Assessor, Examiner or Supervisor Role
- Reference year
- 2017
- Details
- PhD Supervisor. Ongoing Postgraduate Students: ¿ Xuan Huang, MPhil, Queensland University of Technology (from 2017), Associate supervisor¿ Peiyu Wang, ongoing, PhD, Queensland University of Technology (from 2017), Primary supervisor¿ Patricia O¿Gorman, PhD, ongoing, Queensland University of Technology (from 2017), Associate supervisor¿ Sara Hassan, PhD, ongoing, Queensland University of Technology (from 2017), Primary supervisor¿ Aaron McDonald, ongoing, Queensland University of Technology (from 2017), Associate supervisor¿ Sarah-Louise Ryan, PhD, ongoing, Queensland University of Technology (from 2016), Associate supervisor¿ Renwu Zhou, PhD, ongoing Queensland University of Technology (from 2016), Associate supervisor¿ James Monkman, PhD, ongoing, Queensland University of Technology (from 2016), Associate supervisor ¿ Suganda Bhatia, PhD, ongoing, Queensland University of Technology (from 2016), Primary supervisor¿ Alan Toh, PhD, ongoing, Queensland University of
- Type
- Committee Role/Editor or Chair of an Academic Conference
- Reference year
- 2017
- Details
- CONFERENCE ORGANISATION2017-Member, Organising Committee, Brisbane Breast Cancer Workshop (ECR,MCR), QIMR, August 25, 2017. 2017-Member, Program Committee, 8th International Conference on EMT (TEMTIA-VIII), Dec 7-10, Houston, Tx, USA. 2017-Member, Organizing Committee, OzMRS Metastasis Research Symposium, 15-16 December, 2017; Sydney, Australia (in conjunction with Clinical Oncology Societies of Australia's 44th Annual Scientific Meeting, 13-15 December 2017). 2016- Member, Program Committee, COSA / ANZBCTG Annual Scientific Meeting Gold Coast Convention and Exhibition Centre, 15-17 November, 2016. 2015- Convenor, 7th International EMT Meeting (TEMTIA-VII), Melbourne; Brisbane Diamantina Health Partners Circulating Tumour Cells Symposium, March 24, 2015. 2015-Co-Convenor, Inaugural Queensland EMT Symposium, TRI, Brisbane, Oct 16, 2015; 2nd Thomas Ashworth CTC Symposium, 12 October, 2015; Pullman Hotel, Albert Park, Melbourne. 2015-BDHP TRI CTC Symposium, March 24, 2015,
- Type
- Assessor, Examiner or Supervisor Role
- Reference year
- 2016
- Details
- MEMBERSHIP OF REVIEW PANELS 2016 - NHMRC Centres of Research Excellence Clinical Research Review Panel. 2015-2016 - NBCF Early career researcher fellowship panel. 2012-2014 - Working group (Audit 1) for Cancer Australia¿s National Audits of Cancer Research. 2010-2013 - Peter MacCallum Cancer Centre Research Division Promotion Panel. 2009-2012 - ARC INT-Reviewer.
- Type
- Editorial Role for an Academic Journal
- Reference year
- 2014
- Details
- Associate Editor, Cells Tissues Organs (2014 onwards)
Supervision
Current supervisions
- Portable Nuclear Magnetic Resonance (pNMR) Quantitative Measurement of Biological Tissues
PhD, Associate Supervisor
Other supervisors: Dr Konstantin Momot - Examining G9a as a target in breast cancer metastasis and treatment resistance
PhD, Associate Supervisor - Improving longevity of patient-derived explants to increase utility as a precision medicine functional testing platform
MPhil, Associate Supervisor
Other supervisors: Associate Professor Elizabeth Williams, Associate Professor Laura Bray
Completed supervisions (Doctorate)
- Functional Roles of EMP-Associated Targets in Breast Cancer Models (2021)
- Identification and Functional Characterisation of TGFB - Regulated and Cell Surface Candidates in Pancreatic Cancer (2021)
- EMT & MET: Underpinning the Phenotypic Plasticity and Chemoresistance in Breast Cancer (2020)
- Direct and Indirect Activation of Biological Objects Using Cold Atmospheric Plasma (2019)
- Targeting the Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-kB) Pathway to Overcome Cisplatin-Resistance in Non-Small Cell Lung Cancer (2019)
Completed supervisions (Masters by Research)
Supervision topics
The supervisions listed above are only a selection.