1330427
Adjunct Professor
Flavia Huygens
Faculty of Health,
School of Biomedical Sciences
Biography
Research theme:Environment, Food, Health
Research discipline:
Cell and Molecular Biosciences
Research areas
Bioinformatics approach to microbial source tracking in environmental water: Application of the "Minimum SNPs" data mining software program as a genetic fingerprinting tool used to track microbial populations in water sources. High-resolution DNA-melt analysis as a genetic fingerprinting tool to classify bacterial populations: Analysis of tandem-repeat DNA sequences and single-nucleotide polymorphisms present in bacterial genomes by high-resolution melt analysis. Molecular characterisation of intestinal micro-organisms associated with Crohn's disease: Real-time quantitative PCR analysis of microbial organisms present in patients diagnosed with Crohn's disease. Microbial Genotyping Sub-Program Cooperative Research Centre for Diagnostics: Application of the software program "Minimum SNPs" to identify sets of highly informative single nucleotide polymorphisms present in comparative genomic databases of bacterial organisms. Genetic fingerprinting of Staphylococcus aureus using highly informative (high D-value) single nucleotide polymorphisms.
Areas of expertise
- Clinical Microbiology
- Molecular Microbiology
- Bioinformatics
- Genomics
- Novel antimicrobial agents
Personal details
Positions
- Adjunct Professor
Faculty of Health,
School of Biomedical Sciences
Keywords
Bacterial genomics, Bacterial virulence, DNA diagnostics, Antibiotic resistance, Infectious diseases, Bioinformatics, Metagenomics, Microbial biotechnology, Microbial source tracking, Water quality
Research field
Medical microbiology, Microbiology, Medical biotechnology
Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2020
Qualifications
- Ph.D (University of Pretoria)
- MMedSci (Medical Microbiology) (University of Pretoria)
- Post Graduate Certificate in Higher Education (University of Queensland)
- BSc(Agric) Microbiology (University of Pretoria)
Professional memberships and associations
- FASM
Teaching
Teaching discipline: Cell and Molecular Biosciences
Publications
- Huygens, F., Bamber, J., Nimmo, G., Munckhof, W., Schooneveldt, J., Harrison, B., McMahon, J. & Giffard, P. (2006). Staphylococcus Aureus Genotyping Using Novel Real-Time PCR Formats. Journal of Clinical Microbiology, 44(10), 3712–3719. https://eprints.qut.edu.au/7673
- Huygens, F., Stephens, A., Nimmo, G. & Giffard, P. (2004). mecA Locus Diversity in Methicillin-Resistant Staphylococcus Aureus Isolates in Brisbane, Australia, and the Development of a Novel Diagnostic Procedure for the Western Samoan Phage Pattern Clone. Journal of Clinical Microbiology, 42(5), 1947–1955. https://eprints.qut.edu.au/7676
- Giffard, P., Huygens, F., Stephens, A. & Bamber, J. (2008). High-resolution melting analysis of the spa Repeat region of Staphylococcus aureus. Clinical Chemistry, 54(2), 432–436. https://eprints.qut.edu.au/13696
- Stephens, A., Huygens, F., Bamber, J., Price, E., Nimmo, G., Schooneveldt, J., Munckhof, W. & Giffard, P. (2006). Methicillin-Resistance Staphylococcus Aureus Genotyping using a Small Set of Polymorphisms. Journal of Medical Microbiology, 55(1), 43–51. https://eprints.qut.edu.au/7678
- Costello, M. & Huygens, F. (2011). Diversity of community acquired MRSA carrying the PVL gene in Queensland and New South Wales, Australia. European Journal of Clinical Microbiology and Infectious Diseases, 30(10), 1163–1167. https://eprints.qut.edu.au/41424
- Rayner, R., Savill, J., Hafner, L. & Huygens, F. (2015). Modified MLVA for genotyping Queensland invasive Streptococcus pneumoniae. PLoS One, 4(10), 1–15. https://eprints.qut.edu.au/83976
- Rayner, R., Savill, J., Hafner, L. & Huygens, F. (2015). Genotyping Streptococcus pneumoniae. Future Microbiology, 10(4), 653–664. https://eprints.qut.edu.au/83975
- Kleinschmidt, S., Huygens, F., Faoagali, J., Rathnayake, I. & Hafner, L. (2015). Staphylococcus epidermidis as a cause of bacteremia. Future Microbiology, 10(11), 1859–1879. https://eprints.qut.edu.au/91237
- Rathnayake, I., Hargreaves, M. & Huygens, F. (2011). Genotyping of Enterococcus faecalis and Enterococcus faecium isolates by use of a set of eight single nucleotide polymorphisms. Journal of Clinical Microbiology, 49(1), 367–372. https://eprints.qut.edu.au/39076
- Sheludchenko, M., Huygens, F. & Hargreaves, M. (2011). Human-specific E. coli single nucleotide polymorphism (SNP) genotypes detected in a South East Queensland waterway, Australia. Environmental Science & Technology, 45(24), 10331–10336. https://eprints.qut.edu.au/47141
QUT ePrints
For more publications by Flavia, explore their research in QUT ePrints (our digital repository).
Supervision
Completed supervisions (Doctorate)
- Investigating the Role of Smchd1 in Control of Clustered Protocadherin Expression (2016)
- Investigating the Population Structure of Queensland Invasive Streptococcus Pneumoniae Isolates in Children: Using a Modified Multi-Locus Variable Number of Tandem Repeat Analysis and a Novel Minimum SNPs Capsular Typing Method (2015)
- B-Lactamase-Mediated Resistance to Antimicrobials: The Relationship Between Genotype and Phenotype (2014)
- Characteristics of Nontuberculous Mycobacteria from a Municipal Water Distribution System and their Relevance to Human Infections (2013)
- Metabolic and Ecological Study of Environmental Pentose Utilizing Bacteria (E-PUB) (2012)
- Molecular characterisation of environmental enterococci derived from water samples and assessment of associated public health hazards (2012)
- Development and validation of novel methods for microbial source tracking based on Escherichia coli as an indicator of water quality (2011)
- Development of Rapid and Highly Resolving Combinatorial Genotyping Schemes for Campylobacter Jejuni and Campylobacter Coli (2010)
- The Development of Rapid Genotyping Methods for Methicillin-Resistant Staphylococcus Aureus (2008)
- Development of Novel Combinatorial Methods for Genotyping the Common Foodborne Pathogen Campylobacter jejuni (2007)
The supervisions listed above are only a selection.