1336863
Dr Kevin Dudley
Faculty of Science,
School of Biology & Environmental Science
Biography
Dr. Kevin Dudley is an emerging researcher in the fields of epigenetics and genomics. After completing his PhD focused on cancer epigenetics, his research expanded to cover a wide range of biological phenomena, including the developmental origins of disease and the molecular mechanisms of learned behaviours.Since joining QUT's Central Analytical Research Facility in 2013, Kevin has been pivotal in providing genomics-related research support. Recently, he has been investigating epigenetic mechanisms in Helicoverpa armigera, a globally significant agricultural pest. Kevin's work in epigenetics also extends to diverse plant, animal, and microbial systems, with a primary goal of advancing the application of epigenetics in bioproduction, biosurveillance, and environmental sensing.
Using cutting-edge technologies such as long-read sequencing, proteomics, and single-cell genomics, Kevin is focused on developing bioinformatics analysis pipelines tailored for new model species, and combining omics datasets for high-resolution molecular phenotyping. As an advocate for data provenance and FAIR data principles, he highlights the importance of collecting comprehensive metadata to enable data re-use, fostering collaboration and advancing scientific knowledge.
Personal details
Positions
- Research Officer (Genomics)
Faculty of Science,
School of Biology & Environmental Science
Keywords
Epigenetics, Genomics, Bioinformatics, DNA Methylation, Transcriptomics, Proteomics, Cyberomics
Research field
Bioinformatics and computational biology, Agricultural biotechnology, Biochemistry and cell biology
Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2020
Qualifications
- PhD (University of Keele, Staffordshire (UK))
Publications
- Royle, J., Hurwood, D., Sadowski, P. & Dudley, K. (2024). Non-CG DNA methylation marks the transition from pupa to adult in Helicoverpa armigera. Insect Molecular Biology. https://eprints.qut.edu.au/249012
- Mu, B., Sadowski, P., Te'o, J., Patel, B., Pathiraja, N. & Dudley, K. (2024). Identification and characterisation of moderately thermostable diisobutyl phthalate degrading esterase from a Great Artesian Basin Bacillus velezensis NP05. Biotechnology Reports, 42. https://eprints.qut.edu.au/249013
- Paramasivan, S., Ashick, M., Dudley, K., Satake, N., Mills, P., Sadowski, P. & Nagaraj, S. (2024). VPBrowse: Genome-based representation of MS/MS spectra to quantify 10,000 bovine proteins. Proteomics. https://eprints.qut.edu.au/247948
- James-Pearson, L., Dudley, K., Te'o, V. & Patel, B. (2023). A hot topic: thermophilic plastic biodegradation. Trends in Biotechnology, 41(9), 1117–1126. https://eprints.qut.edu.au/243551
- Ranawaka, B., An, J., Lorenc, M., Jung, H., Sulli, M., Aprea, G., Roden, S., Llaca, V., Hayashi, S., Asadyar, L., LeBlanc, Z., Ahmed, F., Naim, F., Bolzan De Campos, S., Cooper, T., Fenselau de Felippes, F., Dong, P., Zhong, S., Garcia-Carpintero, V., Orzaez, D., Dudley, K., Bombarely, A., Bally, J., Winefield, C., Giuliano, G. & Waterhouse, P. (2023). A multi-omic Nicotiana benthamiana resource for fundamental research and biotechnology. Nature Plants, 9(9), 1558–1571. https://eprints.qut.edu.au/241500
- Ashwood, L., Elnahriry, K., Stewart, Z., Shafee, T., Naseem, M., Szanto, T., van der Burg, C., Smith, H., Surm, J., Undheim, E., Madio, B., Hamilton, B., Guo, S., Wai, D., Coyne, V., Phillips, M., Dudley, K., Hurwood, D., Panyi, G., King, G., Pavasovic, A., Norton, R. & Prentis, P. (2023). Genomic, functional and structural analyses elucidate evolutionary innovation within the sea anemone 8 toxin family. BMC Biology, 21. https://eprints.qut.edu.au/240583
- Philips, J., Dudley, K., Waterhouse, P. & Hellens, R. (2019). The rapid methylation of T-DNAs upon agrobacterium inoculation in plant leaves. Frontiers in Plant Science, 10, 1–17. https://eprints.qut.edu.au/127853
- Nagalingam, K., Lorenc, M., Manoli, S., Cameron, S., Clarke, A. & Dudley, K. (2018). Chromatin immunoprecipitation (ChIP) method for non-model fruit flies (Diptera: Tephritidae) and evidence of histone modifications. PLoS One, 13(3), 1–13. https://eprints.qut.edu.au/223793
- Rotllant, G., Nguyen, T., Sbragaglia, V., Rahi, M., Dudley, K., Hurwood, D., Ventura, T., Company, J., Chand, V., Aguzzi, J. & Mather, P. (2017). Sex and tissue specific gene expression patterns identified following de novo transcriptomic analysis of the Norway lobster, Nephrops norvegicus. BMC Genomics, 18, 1–14. https://eprints.qut.edu.au/110293
- Philips, J., Eftekhari, F., Lorenc, M., Dudley, K., Hellens, R. & Waterhouse, P. (2017). The widely used Nicotiana benthamiana 16c line has an unusual T-DNA integration pattern including a transposon sequence. PLoS One, 12(2), 1–9. https://eprints.qut.edu.au/103951
QUT ePrints
For more publications by Kevin, explore their research in QUT ePrints (our digital repository).
Supervision
Looking for a postgraduate research supervisor?
I am currently accepting research students for Honours, Masters and PhD study.
- Genome to phenome: exploiting multi-omics and deep learning strategies to decipher importance of isoforms in health and behaviour
- Uncovering the dark transcriptome and proteome with long-read sequencing
You can browse existing student topics offered by QUT or propose your own topic.
Current supervisions
- Application of Long-Read Sequencing to Study the Role of DNA Methylation on Isoform Expression During Helicoverpa armigera Development
PhD, Principal Supervisor
Other supervisors: Dr Pawel Sadowski - Bioprospecting, and Characterization of Plastic and Plasticiser Degrading Enzymes from Great Australian Artesian Basin Thermophiles for Biorecycling and Bioremediation
PhD, Principal Supervisor
Other supervisors: Dr Pawel Sadowski, Adjunct Associate Professor Junior Te'o
Completed supervisions (Doctorate)
- Characterisation of the Australian Great Artesian Basin's Caldaquabacillus species and potential role in thermophilic plastic biodegradation (2023)
- Improving SWATH-MS data analysis using multi-omics approach (2022)
- Microbial colonisation of low-quality fodders in the bovine rumen (2022)
- The Organisation and Epigenetic Landscape of the Nicotiana Benthamiana Genome (2022)
- Functional Characterisation of DNA Methylation in the Pest Species Helicoverpa armigera (2020)
- Epigenetic Fate of T-DNAs During the Early Stages of Agrobacterium Infection (2019)