QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 121 matching student topics
Displaying 13–24 of 121 results
BIOM04 - Unravelling the function of PSA variants in prostate cancer
OverviewProstate cancer (PCa) is the second-most common cancer in men. Prostate-specific antigen (PSA) encoded by the KLK3 gene is the only FDA-approved PCa biomarker for PCa. As a serine protease, PSA can also regulate multiple functions involved in PCa progression and metastasis and is summarised in our recent publications. Immunotherapies, including PSA-targeting therapies, have shown modest improvement in survival, for only a subset of metastatic PCa patients. Not much is known on the immunoregulatory role of PSA or its variants, …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
PHSW01 - A systematic review of internet-based interventions for supporting teachers’ mental health and wellbeing
The teaching profession is a rewarding yet intensive occupation, with teachers being at increased risk of mental health disorders. Poor mental health does not only affect the wellbeing of teachers but can also have ramifications on the health and wellbeing of students with whom teachers interact (Harding et al., 2019). Although there is a large body of research that focuses on student mental health and wellbeing, less attention has been given to understanding mental health interventions targeting teachers. Furthermore, despite …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Public Health and Social Work
Dietary counselling for nutrition-impacting symptoms during cancer treatment
Nutrition-impacting symptoms contribute to decreased quality of life and food intake, and subsequent malnutrition and decreased willingness to commence or complete cancer treatment, which all compromise survival. Evidence exists to support the role of dietary counselling for malnutrition during cancer treatment; however, less is known about the role of dietary counselling for nutrition-impacting symptoms that lead to the development of malnutrition.This systematic review project will synthesise available evidence on the effect of dietary counselling interventions on nutrition-impacting symptoms (e.g., fatigue, …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Nursing
- Research centre(s)
- Centre for Healthcare Transformation
Cancer and Palliative Care Outcomes Centre
The benefits of custom fit compression garments on markers of performance and recovery
Cape Bionics has its foundations in the aerospace industry in the design of compression suits worn by astronauts on the international space station. The research which underpinned the design of these space suits has now been applied to sport as a means of improving performance and recovery in elite athletes.For compression garments to be effective they must fit perfectly and apply specific pressure regimes. Cape Bionics use technology from the medical and aerospace industry to provide custom fit compression garments …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Human-machine interface (HMI) design to manage driver engagement in automated vehicles
We are seeking an enthusiastic and dedicated individual to join the Empathic Machines project as an HCI/HMI PhD Researcher. This interdisciplinary research project, conducted in collaboration with Queensland University of Technology (QUT) and Seeing Machines, aims to explore the concept of empathic machines in the context of driver monitoring systems (DMS) and automated driving. The successful candidate will contribute to advancing the understanding of human-machine interaction, interface design, and attention sharing to enhance safety and user experience in automated vehicles.A …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Psychology and Counselling
- Research centre(s)
-
Centre for Future Mobility
Understanding human behaviour during automated driving
We are seeking a highly motivated and talented Vision Science and Human Factors PhD Researcher to join an interdisciplinary research project, conducted in collaboration with Queensland University of Technology (QUT) and industry partner Seeing Machines—world leader in human-machine interaction and an industry leader in artificial intelligence (AI), that enable machines to see, understand and assist the people who are using them.A PhD scholarship is available for this project.Learn more about the scholarshipOur program offers:World-class research environment: immerse yourself in a …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Clinical Sciences
- Research centre(s)
-
Centre for Vision and Eye Research
Targeting leptin's signalling axis to prevent treatment resistance in prostate cancer
Advanced prostate cancer (PCa) is a leading cause of cancer-associated death in Australian men. Anti-androgens, which exploit the tumour’s reliance on androgens for its growth & spread, offer temporary remission in advanced PCa patients, but due to treatment resistance, fail to be curative. A further complication of anti-androgens is that they trigger a deleterious suite of metabolic side-effects resembling obesity/Metabolic syndrome. These symptoms not only impact patient health but promote tumours to be more aggressive & resist treatment. Vital new …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Restoring adiponectin signalling to prevent prostate cancer progression
Advanced prostate cancer (PCa) is a leading cause of cancer-associated death in Australian men. Anti-androgens, which exploit the tumour’s reliance on androgens for its growth and spread, offer temporary remission in advanced PCa patients, but due to treatment resistance, fail to be curative. A further complication of anti-androgens is that they trigger a deleterious suite of metabolic side-effects resembling obesity/Metabolic syndrome. These symptoms not only impact patient health but promote the tumour to be more aggressive and resist treatment. Vital …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Characterising the role of PARPs in DNA repair and cancer therapy
The genome of our cells is damaged multiple times each day, by various factors including sunlight and reactive oxygen species. In order for the DNA damage response to be efficient, our cells utilise highly coordinated repair pathways that function accurately and rapidly throughout the damaged cell. Cells that do not repair DNA damage correctly will accumulate damage and display increased genomic instability, which is a key hallmark of cancer cells, promoting their survival and rapid growth. DNA repair pathways are …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Characterise a novel DNA repair protein as a target for cancer therapies
Data generated in the lab has identified a novel DNA repair protein previously described as a key protein in HSP70/90 complexes. Many pathways of tumourigenesis are mediated by Heat Shock Proteins and HSP70/90 are found significantly upregulated in ovarian cancers. The targeting of HSP70/90 are an emerging therapeutic avenue for the treatment of ovarian cancer. Supporting this, an inhibitor of HSP90 has been shown to sensitise breast cancer cells to PARP inhibitors and paclitaxel.Our preliminary data indicates that this new …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Determining the response to PARP inhibitor treatment of ovarian cancer in mouse xenograft model
Our cellular DNA is constantly under threat from both exogenous and endogenous factors. DNA repair pathways function to maintain genomic stability, preventing deleterious mutations that may ultimately lead to cancer initiation. When a tumour forms, it becomes genetically unstable, allowing environmental adaptation. This genetic instability can also result in gene mutations and protein expression alterations that can be targeted to induce cancer-specific cell death (phenomenon also known as synthetic lethality). For example, it has been shown that cells deficient in …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Light, circadian rhythms and Parkinson’s disease
Up to 98% of patients with Parkinson’s Disease (PD) have non-motor symptoms (Poewe et al. Nature Rev Dis 2017, 3: 17013) and of those, circadian and sleep disorders are the most common (for review, Gros & Videnovic. 2020, Clin Geriatr Med 36: 119). These symptoms become increasingly prevalent during the course of PD and are key determinants affecting quality of life, advancement of overall disability and placement in nursing homes (Shapira et al. Nat Rev Neurosci 2017,18:435). Circadian and sleep …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
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