QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.

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Found 121 matching student topics

Displaying 97–108 of 121 results

Illuminating the microbial world using genome-based fluorescence microscopy

Our understanding of microbial diversity on earth has been fundamentally changed by metagenomic characterisation of natural ecosystems. Traditional approaches for visualising microbial communities are time-consuming and provide limited information about the identity of specific microorganisms.The proposed research aims to combine single cell genomics and super resolution microscopy for novel, high-throughput, genome-based techniques to visualise microorganisms, plasmids and viruses, with strain level specificity.The application of these highly scalable approaches will provide comprehensive and unprecedented insight into the fine-scale dynamics and evolution …

Study level
PhD
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Centre for Microbiome Research

Food literacy projects (see description for options)

Food Literacy is a collection of knowledge, skills and behaviours required to plan, manage, select, prepare and eat foods to meet needs and determine food intake. It is the scaffolding that empowers individuals, households, communities or nations to protect diet quality through change and strengthen dietary resilience over time. Areas for further research include, but are not limited to:identifying models to integrated food literacy into dietetic practice e.g. through the Nutrition Care Processdevelop population level indicators for food literacy that …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Exercise and Nutrition Sciences

Food literacy and children

The term food literacy has been empirically for adults, but not for children. It is likely that the definition would differ for children (including adolescents). Possible research projects in this area include but are not limited to:investigating children's role in feeding themselves, in particular the variables that impact on this; and diet quality and food choice pathways that children use, the impact of economic disadvantage, culture, gender, age, geographydefining and conceptualising food literacy for childrenconceptualising food literacy by those developing …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Exercise and Nutrition Sciences

Community and Public Health Nutrition Workforce

The training of a specialised community and public health nutrition (CPHN) workforce assumes they are optimally placed to address food and nutrition issues at a population and community level. However, concomitant with the rise of diet as the leading risk factor contributing to the burden of disease in Australia, has been a dramatic disinvestment in this workforcePermanent, full time nutritionist positions embedded in communities or population settings are few. If an organisation invests in a nutrition intervention it is increasingly …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Exercise and Nutrition Sciences

Aboriginal and Torres Strait Islander food and nutrition projects

Aboriginal and Torres Strait Islander peoples suffer disproportionally from diet-related conditions in Australia. Much current research is deficit based, however this body of work aims to be strengths based. Research projects could include, but are not limited to:a descriptive/explorative of food literacy among Aboriginal and Torres Strait Islander people using an assets based framework exploring positive deviants.a food sovereignty project to describe Aboriginal and Torres Strait Islander foodways. This could be applied to a particular nation group. It could be …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Exercise and Nutrition Sciences

Using a natural β-carboline dimer compound to target metabolic vulnerabilities linked to glycolysis in prostate cancer

Prostate cancer is an androgen dependent cancer and treatments are aimed at preventing activation of the androgen receptor. Part of the development of resistance to therapies involves prostate cancers reprogramming their metabolism to overcome metabolic stress induced by these therapies and support growth and survival. This reprogramming involves increases in the rate of glycolysis and intermediate pathways branching from glycolysis. Previously in our laboratory, the natural compound, beta-carboline dimer, BD, was identified to have potent effects on cell viability, cell …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

A preclinical evaluation pipeline for new antivirulence drugs targeting multidrug resistant bacterial pathogens

A post-antibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century.’ - WHO, 2014 (1). Antimicrobial resistance (AMR) is a global public health priority. If no action is taken, AMR is predicted to kill more people than cancer and diabetes combined by 2050, with 10 million deaths estimated each year and a global cost of up to 100 trillion USD. New therapies to tackle multidrug …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Characterisation of emerging multidrug resistant E. coli pathogens

The last fifteen years have witnessed an unprecedented rise in the rates of antimicrobial resistance among Gram-negative bacteria, described by the World Health organisation as a global health crisis (1). Escherichia coli sequence type 131 (E. coli ST131) is a ‘high-risk’ group of Gram-negative pathogens that have emerged rapidly and spread worldwide in the period of the last 10 years (2). E. coli ST131 strains are typically resistant to multiple classes of antibiotics and cause bloodstream and urinary tract infections …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Identifying protein and metabolite markers of burn injury and trauma

It can be difficult for clinical teams to determine the severity of burn injuries when the patient first presents to the hospital. This is because burn wounds continue to deepen/progress over time, in a process known as burn wound conversion. Some wounds may deepen over days or weeks and require aggressive surgical treatment e.g. grafting, and some wounds don’t progress, stay superficial in depth, and they can be managed conservatively with the application of different bandages or dressings. We have …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Identifying emergent ecosystem responses through genes-to-ecosystems integration at Stordalen Mire

Permafrost thaw induced by climate change is predicted to make up to 174 Pg of near-surface carbon (less than 3m below the surface) available for microbial degradation by 2100. Despite having major implications for human health, prediction of the magnitude of carbon loss as carbon dioxide (CO2) or methane (CH4) is hampered by our limited knowledge of microbial metabolism of organic matter in these environments.Genome-centric meta-omic analysis of microbial communities provides the necessary information to examine how specific lineages transform …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Centre for Microbiome Research

Characterising drivers of melanoma cell heterogeneity

Tumour cell heterogeneity is linked to tumour progression through the generation of divergent cellular behaviours such as proliferation, survival, invasion and therapy resistance. Crucially, conventional and targeted therapies generally only target highly proliferative cells in tumours leading to initial tumour regression, however alternative sub-populations underpin the return of treatment refractory disease and facilitate metastatic spread. Our laboratory is focused on understanding the regulatory drivers of cellular plasticity in melanoma to better understand progression and metastatic spread of this disease and …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Characterisation of a novel protein co-amplified with the n-MYC oncogene

The MYCN oncogene is amplified in a number of tumour types, including Neuroblastoma (NB) and Neuroendocrine Prostate Cancer (NEPC), where it is associated with worse patient prognosis, as compared to non-amplified tumours. However, the high expression of MYCN (encoding the n-MYC protein) alone in non-amplified tumours is associated with better patient prognosis and less aggressive disease. This suggests that other genes co-expressed in MYCN amplified tumours may be responsible for mediating the aggressive traits of n-MYC. Our team has identified …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)
Centre for Genomics and Personalised Health

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