QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 171 matching student topics
Displaying 145–156 of 171 results
The efficacy of Mental Health First Aid (MHFA) training in community sport
Organised sport is primarily community based in Australia; and the benefits of sport participation to individuals and communities are well documented. However, there is also evidence that participating in organised high-performance sporting programs is associated with psychological distress, elevated relative to community norms, which would usually warrant a need for care by a health professional. As such a case for improvement in mental health education and practice in sporting communities exists.Mental Health First Aid (MHFA) is a standardised, psychoeducational programme …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Exercise and Nutrition Sciences
Therapeutic opportunities targeting epigenetic-metabolism crosswalks in cancer
Epigenetic and metabolic pathways in cancer cells are highly interconnected. Epigenetic landscape in cancer cells is modified by oncogene-driven metabolic changes. Metabolites modulate the activities of epigenetic modifying enzymes to regulate the expression of specific genes. Conversely, epigenetic deregulation that occurs in cancer affect the expression of metabolic genes, thereby altering the metabolome. These changes all coordinately enhance cancer cell proliferation, metastasis and therapy resistance.The overall aim of the project is to understand the link between the activity of epigenetic …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Spatial localisation of immunoglobulin A in the gastrointestinal tract.
Blood cancers, which include leukaemia, lymphoma and myeloma account for 10% of all cancers and 9.4% of cancer deaths. Stem cell transplantation (SCT) is the predominant curative therapy for these diseases. However, a major complication is graft-versus-host disease (GVHD) in which the gastrointestinal (GI) tract, skin, lung and liver are preferentially damaged by the transplanted donor immune system, limiting the therapeutic potential of this treatment. Thus, there is a pressing need for new treatment approaches to improve transplant outcome for …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Characterisation of melanoma cell membranes to identify novel drug targets
Cell membrane structure and function are altered during tumour development, but to date comprehensive studies on the characterisation of cell membranes of a given cancer are scarce, or are only focused on a particular property (e.g. overall charge, global lipid composition, or specific lipid). In preliminary work we compared the lipidome (i.e. the lipid profile) of a panel of cells, and found the lipid composition of model melanoma cells to be distinct from that of other cancerous and non-cancerous cells. …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Development of peptides as therapeutics to treat drug-resistant metastatic melanoma
Melanoma is a very aggressive cancer due to its metastatic potential, and the third most common in Australia. Many patients with metastatic melanoma have strong side effects, do not respond, or develop resistance to current therapies, which results in low survival rate (26% in 5-years). This project aims at developing a new class of therapeutic leads to tackle drug-resistance in metastatic melanoma.Currently, the preferred first-line regimen given to patients with metastatic melanoma is immunotherapy with antibodies (i.e. ipilimumab and nivolumab), …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Systematic evaluation towards the analysis of open-source supply chain on ML4SE tasks
Applying machine learning algorithms to source code related SE task is rapidly developing and attracts the attention from both researchers and industry engineers. While there are many program languages available, applying such techniques, i.e., the representation learning models, for different languages may achieve different performance. Particularly, they all have their own strict syntax, which determines the abstract syntax tree. Thus, a lot of different open-source supply chain are available, for example the parsing tools are used to build AST from …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Science
- School
- School of Computer Science
Improving the resilience of older masonry building roofs against winds and cyclones
Wind and cyclonic actions are important in the design of new buildings in many Australian regions including in QLD. Cyclone Tracy in NT proved that older masonry building were particularly vulnerable to cyclonic actions, and the even resulted in the improvement of construction codes.However, there are many buildings that predate the introduction of modern codes. These buildings may be vulnerable to wind and cyclonic actions. This project has been designed to study the wind vulnerability of older masonry buildings and …
- Study level
- Honours
- Faculty
- Faculty of Engineering
- School
- School of Civil and Environmental Engineering
- Research centre(s)
- Centre for Materials Science
Centre for the Environment
Antibiotic-loaded polymer nanoparticulate inhaled formulations against lung infections associated with COPD and CF
Lower respiratory tract infections (LRTIs) are one of the fatal diseases of the lungs that have severe impacts on public health especially the Indigenous people. The currently available antibiotics administered orally for the treatment of LRTIs need high doses with frequent administration and cause dose-related adverse effects.To overcome this problem, we will investigate the development of antibiotic-loaded polymer nanoparticles (NPs) for potential pulmonary delivery from dry powder inhaler (DPI) formulations. This study will address the release profile of the antibiotic …
- Study level
- PhD
- School
- School of Clinical Sciences
- Research centre(s)
- Centre for Materials Science
Centre for Immunology and Infection Control
Using mathematics to understand multiple sclerosis: what causes the immune system to attack the brain?
Every day, we use our bodies to move, think, talk and eat, but for people with multiple sclerosis (MS) these tasks can be virtually impossible. MS is a chronic disease which develops because the immune system has started to attack the nerve cells in the brain. This causes the degradation of parts of the brain and irreversible impairment in physical and mental activity. Unfortunately, this disease has no cure, and while considerable therapeutic advances against this disease have been achieved, …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
Avatar customisation for diversity training in virtual reality
Avatar representation is found to be crucial for user engagement in various types of applications and user identifications with avatars. This project aims to design and develop an environment where users can customize their avatars by looking at a virtual mirror. In this project, where users will be trained in diversity awareness, it is crucial for them to feel like the character who is in the scenario. The outcome of the project will be used in experiments to test the …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Computer Science
Enhancing sonographer work-integrated learning: balancing quality training with workforce demands and student well-being
Sonographers, highly skilled healthcare professionals responsible for essential diagnostic ultrasound services, are currently facing a severe nationwide shortage. The Australasian Sonographers Association reported a deficit of at least 3,000 sonographers in 2019. Training new sonographers involves comprehensive work-integrated learning (WIL), which blends academic knowledge with structured real-world experiences to develop vital clinical skills. However, due to escalating workforce demands, concerns have arisen about potential exploitation of students within workplaces. This exploitation could involve assigning tasks exceeding their capabilities or subjecting …
- Study level
- PhD, Master of Philosophy
- School
- School of Clinical Sciences
Hospital readmission prediction with domain knowledge
The Australian Commission on Safety and Quality in Health Care (the Commission) has highlighted that reducing avoidable hospital readmissions supports better health outcomes, improves patient safety and leads to greater efficiency in the health system. Previous studies have reported that up to 11% of the Emergency (ED) population are "heavy users" with a higher prevalence of psychosocial problems and often co-existing chronic medical conditions. All Australian governments have committed to reforms under the National Health Reform Agreement Addendum,1 and the …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Computer Science
- Research centre(s)
- Centre for Data Science
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