QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 171 matching student topics
Displaying 73–84 of 171 results
Characterising the role of PARPs in DNA repair and cancer therapy
The genome of our cells is damaged multiple times each day, by various factors including sunlight and reactive oxygen species. In order for the DNA damage response to be efficient, our cells utilise highly coordinated repair pathways that function accurately and rapidly throughout the damaged cell. Cells that do not repair DNA damage correctly will accumulate damage and display increased genomic instability, which is a key hallmark of cancer cells, promoting their survival and rapid growth. DNA repair pathways are …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Understanding the genetics of melanoma susceptibility: many roads lead to DNA repair
Repair of the damage caused by mutagens such as UV and reactive oxygen species is vital to prevent cancer and premature aging and accordingly cells have developed a suite of intricate and specific DNA repair pathways. Loss or abnormal function of components of these pathways lead to cancer pre-disposition syndromes for example breast cancer in individuals carrying mutations in the BRCA1 or BRCA2 genes. Understanding the complexities of these DNA repair pathways is vital to efforts aimed at preventing or …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Curtailing corporate tax aggression through uncertain tax benefits
Over the last five years Australia has adopted numerous measures to address aggressive corporate tax practices. A recent addition to these measures (on the 1st of January 2019) is AASB Interpretation 23 - Uncertainty over Income Tax Treatments, which was developed to clarify the treatment of uncertain tax positions. This interpretation requires entities who produce general purpose financial reports (GPFRs) to disclose uncertain tax benefits (UTB) in the notes to their financial statements. Extant literature suggests that UTB disclosures are …
- Study level
- Honours
- Faculty
- Faculty of Business and Law
- School
- School of Accountancy
Robotic maintenance of equipment
Think about the problem of maintaining equipment at remote work sites. How can robotic technology help human maintenance staff to work more safely and productively?
- Study level
- PhD
- Faculty
- Faculty of Engineering
- School
- School of Electrical Engineering and Robotics
Making the most of many models
In the age of Big Data, machine learning methods, and modern statistics the adage "all models are wrong but some are useful" has never been so true. This project will investigate data science approaches where more than one model makes sense for the data. Is it better to choose a single model or is there something to be gained from multiple models?This project will look at variable selection methods, penalised regression, Bayesian model averaging and conformal prediction. The research has …
- Study level
- Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
- Research centre(s)
- Centre for Data Science
Parameter identifiability for stochastic processes in biological systems
Stochastic models are used in biology to account for inherent randomness in many cellular processes, for example gene regulatory networks. Noise is often thought to obscure information, however, there is an increasing understanding that some randomness contains vitally important information about underlying biological processes.When applying these models to interpret and learn from data, unknown parameters in the model need to be estimated. However, not all data will contribute to a given estimation task regardless of the data quantity and quality. …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
- Research centre(s)
- Centre for Data Science
Development of a Microfluidic Gut-Brain Axis Chip
The gut microbiome refers to the collection of micro-organisms that are living symbiotically in the human or animal gastrointestinal tract (defined as the “microbiota”), their genetic material as well as the surrounding environmental habitat. It is now appreciated that the microbiome plays an important role in human health and diseases. Many neurodegenerative diseases, such as Parkinson's Disease have been linked to dysregulation of the gut microbiota. However, it is difficult to study gut-brain axis using animal models due to inter-species …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Centre for Microbiome Research
Modelling and managing uncertain Antarctic species networks
Antarctic ecosystems are complex, and data is limited since it is expensive to collect. Species including penguins, seabirds, invertebrates, mosses, and marine species interact in food webs which can be modelled as mathematical networks. These networks can be large, span across terrestrial and marine systems, and are changing in response to environmental changes.These ecological networks can be modelled using differential equation predator prey models like Lotka-Volterra to describe these interactions. However, the relationships between species are not always known, or …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
- Research centre(s)
- Centre for Data Science
Centre for the Environment
Efficient Parameter Estimation for Stochastic Simulations
Stochastic simulation-based models are routinely used in many areas of science to describe inherent randomness in many real-world systems. Applications include the study of particle physics, imaging if black holes, biochemical processes, the migration of animals, and the spread of infectious diseases. To apply these models to interpret data requires statistical methods to estimate model parameters.Unfortunately, standard statistical techniques are not capable of analysing data using these models. This is largely due to the model likelihood, the probability of the …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
- Research centre(s)
- Centre for Data Science
Aboriginal and Torres Strait Islander food and nutrition projects
Aboriginal and Torres Strait Islander peoples suffer disproportionally from diet-related conditions in Australia. Much current research is deficit based, however this body of work aims to be strengths based. Research projects could include, but are not limited to:a descriptive/explorative of food literacy among Aboriginal and Torres Strait Islander people using an assets based framework exploring positive deviants.a food sovereignty project to describe Aboriginal and Torres Strait Islander foodways. This could be applied to a particular nation group. It could be …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Exercise and Nutrition Sciences
Wearable neuro-imaging and spatial experience
Our built environment changes our brain function. There is considerable interest from many research fields upon the positive and negative health and wellbeing effects of our environments. This research area explores how architectural environments and spaces impact experience and mood using wearable brain-imaging technology.
- Study level
- PhD, Master of Philosophy
- School
- School of Architecture and Built Environment
Reimagining air travel passenger experience
Air travel is poised for systemic transformation due to the advent and implementation of emerging technologies. For example, electric vertical take-off and landing aircraft have the potential to deliver sustainable, efficient, and fast, short-range mobility in urban environments. Advances in fuel and propulsion systems, such as those used in hydrogen electric aircraft, could have broader impact, delivering aspirations of zero carbon aviation.Given the nascent qualities of such technology advances, it is unclear how they will affect passenger experience. Currently, air …
- Study level
- PhD
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
-
Design Lab
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