QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 502 matching student topics
Displaying 457–468 of 502 results
Interaction between pollen proteases and ACE2 receptor of SARS-CoV-2
Pollen allergy is a common seasonal respiratory disease triggered by hypersensitivity to pollen affecting 10-30% of adults and 40% of children, and is a predisposing factor for asthma. Pollens interact with airway epithelium to both stimulate innate immunity and elicit an adaptive immune response.Proteolytic activity is one route that stimulates release of alarmins and pro-inflammatory cytokines from mucosal epithelia. Previous studies have found the expression of Serine/Cysteine (Ser/Cys) proteases in some types of grass pollen grains, but it is not …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Digital inclusion and participation
Working in partnership with industry, government and community organisations, the Digital Inclusion and Participation research program within QUT's Digital Media Research Centre uses innovative digital ethnographic and co-design methods to understand, intervene, and advocate for digital access and literacy as vital elements of social inclusion.We help equip citizens and consumers with the knowledge and skills to confidently, effectively and ethically navigate the increasingly complex digital media environment; and we deliver actionable new knowledge of the structural conditions and circumstances that …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Communication
- Research centre(s)
- Digital Media Research Centre
High-performance scoring of CRISPR targets
The CRISPR-Cas9 technology allows the modification of virtually any gene in any organism of interest. It's generated a lot of interest, both in the research community and the general population.One of the crucial components of CRISPR experiments is the design of the "guide RNAs" that will control where modifications occur. It's vital that the modification is made at the desired location and not elsewhere.We developed a method utilising high-performance computing to efficiently assess the "off-target risk" of each guide RNA …
- Study level
- Honours
- Faculty
- Faculty of Science
- School
- School of Computer Science
- Research centre(s)
- Centre for Data Science
Improving cow fertility: targeting exosome-responsive pathways
Exosomes are small (40-120 nm), stable, lipid bilayer nanovesicles identified in biological fluids (e.g. in Until recently, genetic selection in dairy cows has focused primarily on milk production traits, with very few countries including functional traits such as fertility in selection indices. Poor reproductive efficiency in dairy herds results in fewer calves, reduced milk production, high involuntary culling rates and increased cow maintenance costs. The need for, and utility of, markers of early onset of diseases (or vulnerability to diseases) …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Testing a promising targeted therapeutic for triple-negative breast cancer
Triple-negative breast cancers (TNBC) are negative for Estrogen Receptor, Progesterone Receptor and HER2 expression, are clinically aggressive and cannot be treated with the available hormonal or targeted drugs used for other breast cancer subtypes. TNBC accounts for 15-20% of all invasive breast cancer and patients have increased risk of recurrence, mortality and metastases early during disease progression. There is an urgent clinical need to develop improved treatment strategies for these women since the median survival of patients with metastatic TNBC …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
How many species were saved by national parks?
National parks are the cornerstone of modern conservation efforts. They now cover more than 10% of the Earth’s land surface and are found on every continent and sea.We can prove that these national parks stop human destruction of habitat. We can prove that they benefit the lives and livelihoods of people who visit and surround them. However, we can't yet prove that they have stopped the extinction of a single species. This isn't because we don’t believe that they've helped. …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
A preclinical evaluation pipeline for new antivirulence drugs targeting multidrug resistant bacterial pathogens
A post-antibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century.’ - WHO, 2014 (1). Antimicrobial resistance (AMR) is a global public health priority. If no action is taken, AMR is predicted to kill more people than cancer and diabetes combined by 2050, with 10 million deaths estimated each year and a global cost of up to 100 trillion USD. New therapies to tackle multidrug …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Aerosol presursors in Australian marine environments
Aerosols, tiny solid or liquid particles, play an important role in global climate regulation, firstly, by scattering and absorbing incoming solar radiation and, secondly, by their ability to take up water vapor from the atmosphere and serve as nuclei for cloud droplet formation (Cloud Condensation Nuclei (CCN)).With oceans covering 71% of the Earth’s surface, marine aerosols present a significant proportion of the global aerosol budget. Production of particles in the marine environment occurs via 2 pathways: 1) wave breaking and …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Science
- School
- School of Earth and Atmospheric Sciences
- Research centre(s)
-
Centre for the Environment
Should Australia legislate to allow three parent babies?
In 2015, the United Kingdom legalised a form of in vitro fertilisation (IVF) therapy known as ‘three-parent IVF’ and, less colloquially, mitochondrial replacement therapy (MRT). This IVF procedure is aimed at enabling women who have mitochondrial diseases that would normally be passed down to their offspring to have a healthy child instead. The technique involves removing faulty mitochondria from the intended mother’s egg and replacing them with mitochondria from a generically unrelated woman (by transferring the intended mother's nucleus to …
- Study level
- PhD
- Faculty
- Faculty of Business and Law
- School
- School of Law
- Research centre(s)
-
Australian Centre for Health Law Research
Assessing reef restoration using MARRS Reef Stars on the Great Barrier Reef
The Bait Reef rehabilitation project commenced in early 2021 (site surveys, risk assessments and approval processes) and installation on-site occurred in October 2021. Since installation there has been monitoring of the Reef Stars in June 2022, February 2023, and January 2024.Thermal bleaching impacts in early 2022 and rapid colonisation of the area by soft corals meant that by February 2022 more than 50% of the original coral fragments had died. Subsequently, in August 2023 all dead fragments (still attached to …
- Study level
- PhD, Master of Philosophy, Honours
- School
- School of Earth and Atmospheric Sciences
- Research centre(s)
- Centre for Data Science
Identification and characterisation of IRX4 isoforms as novel targets in prostate cancer
Prostate cancer (PCa) is the second leading cause of cancer-related death in Australian men. There is no cure for advanced prostate cancer patients who develop resistance to currently available treatments. Alternative splicing (AS) is tightly regulated to maintain genomic stability in humans (Liyanage et al 2019). Aberrant RNA splicing of cancer-causing genes has been reported as a major cause of treatment escape in prostate cancer patients. Iroquois-class homeodomain protein 4 (IRX4) is a TALE homeobox transcription factor which has been …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Flexible thermoelectrics for wearable electronics
Advancements in miniaturisation and integration of electronics have recently stimulated the explosive progress in wearable electronics. With increasing practical needs, our analysis has indicated that the market values of wearable electronics are predicted to boost up to US$50B in 2022 and US$72B in 2026. Currently, conventional batteries have limited applications in wearable electronics due to their requirements of frequent replacement/recharge and extra-maintenance. This is especially true in temperature or pressure sensors in some circumstances such as remote-control smart home systems …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Science
- School
- School of Chemistry and Physics
- Research centre(s)
- Centre for Materials Science
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