QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 46 matching student topics
Displaying 25–36 of 46 results
Reducing the environmental impacts of wound care in Qld public hospitals
If Australia’s healthcare system is to achieve net zero emissions by 2050 in line with other countries, all avenues for reducing healthcare waste should be explored. Therefore, there is an urgent need to understand the lifecycles of wound care waste streams and to improve their usage as per the waste management hierarchy. This study aims to investigate both the amount of wound care waste generated as well as disposal behaviours in public wound care clinics in QLD with the overall …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Nursing
- Research centre(s)
- Centre for Healthcare Transformation
Targeting a novel adaptive neovascular response of the tumour microenvironment to treat advanced prostate cancer
Prostate cancer (PCa) is a significant healthcare burden in Australia. Androgen signalling inhibition using androgen receptor (AR) antagonists is the principal systemic therapy for advanced PCa. Androgen receptors (AR) are an attractive therapeutic target due to their elevated expression in tumour epithelial cells and the retention of androgen signalling throughout the disease continuum.However, patients eventually develop resistance to treatment, and PCa cells metastasise to distant bone and visceral organs, representing an incurable stage of the disease. Understanding mechanisms that contribute …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Engineering the prostate tumour microenvironment in organ-on-a-chip systems
Prostate cancer remains one of the leading causes of global death. The tumour microenvironment (TME) including blood vessels, immune cells, fibroblasts, and the extracellular matrix (ECM) possesses disease-specific biophysical and biological factors that are difficult to recapitulate using conventional in vitro cell culture models.The absence of these factors, however, causes cells to display abnormal morphologies, polarisation, proliferation, and drug responses, thereby limiting the ability to translate research findings from traditional cell culture into clinical practice.Recent advances in organ-on-a-chip technology enable …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Spatial profiling of the tumour microenvironment
Lung cancers are the leading cause of cancer related deaths in Australia, with a 5-year survival of 15%. With the emerging success of immune checkpoint blockage leading to durable responses and prolonged survival in 15-40% of cases, there is now a need for predictive biomarkers to guide selection for immunotherapies.The immune contexture of the tumour microenvironment (TME) is an important factor in dictating how well a tumour may respond to immune checkpoint therapies (1). Spatial and immunological composition with cellular …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Blast response and safety assessment of transport tunnels
Transport tunnels are important components of the transport systems in major cities. They can be vulnerable to bomb explosions caused by accidental or deliberate means.This project will evaluate the vulnerability of transport tunnels to credible blast events and the influence of key parameters. We'll then propose measures to mitigate the adverse effects of such explosions to maximise the safety of passengers, infrastructure and transport vehicles.
- Study level
- PhD
- Faculty
- Faculty of Business and Law
- School
- School of Accountancy
Wearable neuro-imaging and spatial experience
Our built environment changes our brain function. There is considerable interest from many research fields upon the positive and negative health and wellbeing effects of our environments. This research area explores how architectural environments and spaces impact experience and mood using wearable brain-imaging technology.
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Architecture and Built Environment
Engineering bioartificial extracellular tumour microenvironments for Osteosarcoma personalised precision oncology
Osteosarcoma (OS) is the most common malignant bone tumour affecting children and adolescents. Importantly, clinical outcomes have not improved for decades, and bone tumours remain to be a leading cause of cancer-related death in adolescents.By identifying ideal treatment approaches for each individual patient, precision oncology has the potential to significantly improve these outcomes. Yet, its widespread application is hindered by a lack of biomaterials that support the reproducible and robust generation of patient-derived osteosarcoma organoids in vitro.Therefore, this project will …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Biomedical Technologies
How do healthy people sleep? Biomechanics, physiology, and environment - what matters most?
In the Westernized world a person typically spends one third of their life in bed, with more time spent sleeping in a bed than in any other single activity. Sleep amount and quality of sleep have a direct impact on mood, behaviour, motor skills and overall quality of life. Yet, despite how important restful sleep is for the body to maintain good health, there is a comparatively small amount of studies evaluating key multi-factorial and biomechanical determinants of restful sleep …
- Study level
- PhD
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Mapping the world: understanding the environment through spatio-temporal implicit representations
Accurately mapping large-scale infrastructure assets (power poles, bridges, buildings, whole suburbs and cities) is still exceptionally challenging for robots.The problem becomes even harder when we ask robots to map structures with intricate geometry or when the appearance or the structure of the environment changes over time, for example due to corrosion or construction activity.The problem difficulty is increased even more when sensor data from a range of different sensors (e.g. lidars and cameras, but also more specialised hardware such as …
- Study level
- PhD
- Faculty
- Faculty of Engineering
- School
- School of Electrical Engineering and Robotics
- Research centre(s)
- Centre for Robotics
Multi-UAV navigation in GPS denied environments
The aim of this research is to develop a framework for multiple Unmanned Aerial Vehicles (UAV), that balances information sharing, exploration, localization, mapping, and other planning objectives thus allowing a team of UAVs to navigate in complex environments in time critical situations. This project expects to generate new knowledge in UAV navigation using an innovative approach by combining Simultaneous Localization and Mapping (SLAM) algorithms with Partially Observable Markov Decision Processes (POMDP) and Deep Reinforcement learning. This should provide significant benefits, …
- Study level
- PhD
- Faculty
- Faculty of Engineering
- School
- School of Electrical Engineering and Robotics
UAV navigation in GPS denied environments
This PhD project aims to develop a framework for unmanned aerial vehicles (UAV), which optimally balances localisation, mapping and other objectives in order to solve sequential decision tasks under map and pose uncertainty. This project expects to generate new knowledge in UAV navigation using an innovative approach by combining simultaneous localisation and mapping algorithms with partially observable markov decision processes. The project’s expected outcomes will enable UAVs to solve multiple objectives under map and pose uncertainty in GPS-denied environments. This …
- Study level
- PhD
- Faculty
- Faculty of Engineering
- School
- School of Electrical Engineering and Robotics
Optimal conservation management in uncertain Antarctic environments
Species and ecosystems in Antarctica are threatened. Optimal biodiversity conservation is an interdisciplinary field combining mathematical modelling and optimisation with ecology and conservation. We can use mathematics to understand the system, model how management actions might impact it, and then optimise which actions should be used. For example, we can explore where protected areas should be placed, how species should be managed, or how tourist impacts should be reduced. However, the complexities of conservation in Antarctica necessitate the application of …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
- Research centre(s)
- Centre for Data Science
Centre for the Environment
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