QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 30 matching student topics
Displaying 1–12 of 30 results
Spatial localisation of immunoglobulin A in the gastrointestinal tract.
Blood cancers, which include leukaemia, lymphoma and myeloma account for 10% of all cancers and 9.4% of cancer deaths. Stem cell transplantation (SCT) is the predominant curative therapy for these diseases. However, a major complication is graft-versus-host disease (GVHD) in which the gastrointestinal (GI) tract, skin, lung and liver are preferentially damaged by the transplanted donor immune system, limiting the therapeutic potential of this treatment. Thus, there is a pressing need for new treatment approaches to improve transplant outcome for …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Tobacco control
As a prime advocate for plain packaging of tobacco products, Professor Matthew Rimmer is engaged in research and public policy work on tobacco control. He is interested in supervising research students working within the field of tobacco control - including in respect of the WHO Framework Convention on Tobacco Control; trade and investment disputes over tobacco control; the plain packaging of tobacco products; restrictions on tobacco advertising, sponsorship, and promotions; generational limitations on smoking; spatial restrictions on smoking; and civil …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Business and Law
- School
- School of Law
- Research centre(s)
-
Australian Centre for Health Law Research
Better an iceberg or a penguin? Relative importance of cultural ecosystem services in Antarctica
The tourism industry is rapidly expanding in Antarctica, increasing by an order of magnitude over the past two decades. The resilience of this industry depends on the resilience of the Antarctic ecosystem but which element of Antarctica is the most important? Is it better a penguin or an iceberg?The proposed study will make use of social media channels to collect data on Antarctica tourism. By assessing photos’ captions and Twitter hashtags, the study aims to determine how frequently terms such …
- Study level
- Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
UAV navigation in GPS denied environments
This PhD project aims to develop a framework for unmanned aerial vehicles (UAV), which optimally balances localisation, mapping and other objectives in order to solve sequential decision tasks under map and pose uncertainty. This project expects to generate new knowledge in UAV navigation using an innovative approach by combining simultaneous localisation and mapping algorithms with partially observable markov decision processes. The project’s expected outcomes will enable UAVs to solve multiple objectives under map and pose uncertainty in GPS-denied environments. This …
- Study level
- PhD
- Faculty
- Faculty of Engineering
- School
- School of Electrical Engineering and Robotics
Investigating the role of Neuropilin-1 in Triple-Negative Breast Cancer metastasis and chemoresistance
Triple-negative breast cancers (TNBC) are negative for Estrogen Receptor, Progesterone Receptor and HER2 expression, are clinically aggressive and are unresponsive to the available hormonal or targeted drugs used for other breast cancer subtypes, so that TNBC patients rely mainly on chemotherapy. TNBC accounts for 15-20% of all invasive breast cancer and patients have increased risk of recurrence, mortality and early metastatic progression. Thus, there is an urgent clinical need to develop improved treatment strategies for TNBC. Neuropilin-1 (NRP1) is a …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Investigating differences in downstream signalling mediated by two isoforms of FGFR2 in endometrial cancer
FGFR2 encodes two alternatively spliced isoforms that differ in their ligand binding domain and the combination of tissue specific expression of these isoforms and tissue specific expression of the FGF ligands is the foundation of normal paracrine signalling. Isoform switching from FGFR2b (inclusion of exon 8) to FGFR2c (inclusion of exon 9) occurs in tumorigenesis as it establishes an autocrine loop in epithelial cancer cells.We have previously published a detailed investigation into differences between wildtype FGFR2b and mutant FGFR2b following …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Investigating immunosuppression downstream of activated FGFR2 in endometrial cancer
FGFR2 encodes two alternatively spliced isoforms that differ in their ligand binding domain and the combination of tissue specific expression of these isoforms and tissue specific expression of the FGF ligands is the foundation of normal paracrine signalling. Isoform switching from FGFR2b (inclusion of exon 8) to FGFR2c (inclusion of exon 9) occurs in tumorigenesis as it establishes an autocrine loop in epithelial cancer cells. Our lab has reported that FGFR2 activation by mutations or isoform switching is associated with …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Investigating genetic variants involved in Wilson disease and copper metabolism using genome editing
Wilson disease (WD) is a genetic disorder of copper metabolism. It can present with hepatic and neurological symptoms, due to copper accumulation in the liver and brain (1). WD is caused by compound heterozygosity or homozygosity for mutations in the copper transporting P-type ATPase gene ATP7B. Over 700 ATP7B genetic variants have been associated with WD. Estimates for WD population prevalence vary with 1 in 30,000 generally quoted. Early diagnosis and treatment are important for successful management of the disease. …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
Investigation of genetic factors that contribute to concussion and its outcomes
The health outcomes from traumatic brain injuries (TBIs) and concussion depend on the nature of the injury, but response also varies greatly between individuals, suggesting that genetic factors may play a role. In particular, due to effects of head trauma on balances of ions, neurotransmitters and energy use in the brain, there is suggestion that variation in the genes that encode proteins involved in these pathways, e.g. ion channels, may affect the risk of, as well as response to a …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Investigating DNA repair mechanisms in aging adult stem cells
When we age the DNA repair systems of our cells become down regulated. This results in reduced DNA repair capacity, enhanced rates of mutation load and may lead to the development of chronic aging-associated diseases including osteoporosis, Alzheimer's and cancer(1). So it is no surprise that genome instability and stem cell exhaustion, which also strongly correlates with the accumulation of DNA damage, are considered hallmarks of aging(2).However, we still lack a clear understanding on how the decrease in DNA repair …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Investigating community advocacy in response to aircraft noise pollution in Brisbane: an ethnographic study
The flight path design and community engagement practices associated with Brisbane Airport have long been criticised for prioritising profit over community wellbeing, leading to excessive aircraft noise pollution. These issues have now amounted to a federal Senate Inquiry and an investigation by the Commonwealth Ombudsman.This PhD research project aims to explore the dynamics between Brisbane Airport and the affected residential communities across more than 220 suburbs, drawing inspiration from a similar study conducted into the social engineering practices of Schiphol …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
- Digital Media Research Centre
Design Lab
Investigating integration of climate change adaptation policies across government levels
Climate change poses an unprecedented global challenge, and its impact is profoundly felt at the local level. The pressing need for effective adaptation strategies requires a nuanced understanding of how local governments navigate and integrate policies at various administrative tiers. Our research project delves into the pivotal question of how local governments align with regional, state, and national climate change adaptation policies, offering a crucial lens into the challenges and opportunities that emerge at the intersection of policy and planning.This …
- Study level
- Honours
- Faculty
- Faculty of Engineering
- School
- School of Architecture and Built Environment
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