QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 29 matching student topics
Displaying 13–24 of 29 results
Investigating immunosuppression downstream of activated FGFR2 in endometrial cancer
FGFR2 encodes two alternatively spliced isoforms that differ in their ligand binding domain and the combination of tissue specific expression of these isoforms and tissue specific expression of the FGF ligands is the foundation of normal paracrine signalling. Isoform switching from FGFR2b (inclusion of exon 8) to FGFR2c (inclusion of exon 9) occurs in tumorigenesis as it establishes an autocrine loop in epithelial cancer cells. Our lab has reported that FGFR2 activation by mutations or isoform switching is associated with …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Investigating the role of Neuropilin-1 in Triple-Negative Breast Cancer metastasis and chemoresistance
Triple-negative breast cancers (TNBC) are negative for Estrogen Receptor, Progesterone Receptor and HER2 expression, are clinically aggressive and are unresponsive to the available hormonal or targeted drugs used for other breast cancer subtypes, so that TNBC patients rely mainly on chemotherapy. TNBC accounts for 15-20% of all invasive breast cancer and patients have increased risk of recurrence, mortality and early metastatic progression. Thus, there is an urgent clinical need to develop improved treatment strategies for TNBC. Neuropilin-1 (NRP1) is a …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Investigating differences in downstream signalling mediated by two isoforms of FGFR2 in endometrial cancer
FGFR2 encodes two alternatively spliced isoforms that differ in their ligand binding domain and the combination of tissue specific expression of these isoforms and tissue specific expression of the FGF ligands is the foundation of normal paracrine signalling. Isoform switching from FGFR2b (inclusion of exon 8) to FGFR2c (inclusion of exon 9) occurs in tumorigenesis as it establishes an autocrine loop in epithelial cancer cells.We have previously published a detailed investigation into differences between wildtype FGFR2b and mutant FGFR2b following …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Investigating genetic variants involved in Wilson disease and copper metabolism using genome editing
Wilson disease (WD) is a genetic disorder of copper metabolism. It can present with hepatic and neurological symptoms, due to copper accumulation in the liver and brain (1). WD is caused by compound heterozygosity or homozygosity for mutations in the copper transporting P-type ATPase gene ATP7B. Over 700 ATP7B genetic variants have been associated with WD. Estimates for WD population prevalence vary with 1 in 30,000 generally quoted. Early diagnosis and treatment are important for successful management of the disease. …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
Investigating effectiveness of local government social media channels
As social media becomes more intertwined into our daily lives, having an online presence on social media has become common not just in the private but also in the public sectors. The use of social media in local governments has shown great potential in terms of improving the efficiency and effectiveness of citizen-government communication. It has also been effective in terms of increasing citizen engagement and participation. Therefore, this research project seeks to discover how do local governments leverage the …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Engineering
- School
- School of Architecture and Built Environment
Investigating integration of climate change adaptation policies across government levels
Climate change poses an unprecedented global challenge, and its impact is profoundly felt at the local level. The pressing need for effective adaptation strategies requires a nuanced understanding of how local governments navigate and integrate policies at various administrative tiers. Our research project delves into the pivotal question of how local governments align with regional, state, and national climate change adaptation policies, offering a crucial lens into the challenges and opportunities that emerge at the intersection of policy and planning.This …
- Study level
- Honours
- Faculty
- Faculty of Engineering
- School
- School of Architecture and Built Environment
Investigating community advocacy in response to aircraft noise pollution in Brisbane: an ethnographic study
The flight path design and community engagement practices associated with Brisbane Airport have long been criticised for prioritising profit over community wellbeing, leading to excessive aircraft noise pollution. These issues have now amounted to a federal Senate Inquiry and an investigation by the Commonwealth Ombudsman.This PhD research project aims to explore the dynamics between Brisbane Airport and the affected residential communities across more than 220 suburbs, drawing inspiration from a similar study conducted into the social engineering practices of Schiphol …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
- Digital Media Research Centre
Design Lab
Medical litigation, medical law and compensation for medical negligence
Tina Cockburn is interested in supervising PhD students in the area of patient safety law — focusing on medical litigation and compensation for medical negligence, communication of information to patients (including consent and post treatment open disclosure), regulation of health care professionals and the regulation of innovative medical treatment and new technologies.
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Business and Law
- School
- School of Law
- Research centre(s)
-
Australian Centre for Health Law Research
Multi-UAV navigation in GPS denied environments
The aim of this research is to develop a framework for multiple Unmanned Aerial Vehicles (UAV), that balances information sharing, exploration, localization, mapping, and other planning objectives thus allowing a team of UAVs to navigate in complex environments in time critical situations. This project expects to generate new knowledge in UAV navigation using an innovative approach by combining Simultaneous Localization and Mapping (SLAM) algorithms with Partially Observable Markov Decision Processes (POMDP) and Deep Reinforcement learning. This should provide significant benefits, …
- Study level
- PhD
- Faculty
- Faculty of Engineering
- School
- School of Electrical Engineering and Robotics
Exploring green infrastructure optimisation for climate change adaptation and mitigation
Green infrastructure refers to public and private green spaces in cities that provide water cycle benefits. These green spaces range in the range from single trees on city streets to urban parks, and waterway walkways. Some are natural, such as the remains of native plants, while others are more geometric, for example green roofs and green walls. Green infrastructure can increase the sustainability and vitality of cities through benefits such as greening and cooling, water quality, and managing hotter weather. …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Engineering
- School
- School of Architecture and Built Environment
Flexible thermoelectrics for wearable electronics
Advancements in miniaturisation and integration of electronics have recently stimulated the explosive progress in wearable electronics. With increasing practical needs, our analysis has indicated that the market values of wearable electronics are predicted to boost up to US$50B in 2022 and US$72B in 2026. Currently, conventional batteries have limited applications in wearable electronics due to their requirements of frequent replacement/recharge and extra-maintenance. This is especially true in temperature or pressure sensors in some circumstances such as remote-control smart home systems …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Science
- School
- School of Chemistry and Physics
- Research centre(s)
- Centre for Materials Science
Robot learning for navigation, interaction, and complex tasks
How can robots best learn to navigate in challenging environments and execute complex tasks, such as tidying up an apartment or assist humans in their everyday domestic chores?Often, hand-written architectures are based on complicated state machines that become intractable to design and maintain with growing task complexity. I am interested in developing learning-based approaches that are effective and efficient and scale better to complicated tasks.Especially learning based on semantic information (such as extracted by the research in semantic SLAM above), …
- Study level
- PhD
- Faculty
- Faculty of Engineering
- School
- School of Electrical Engineering and Robotics
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