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Found 66 matching student topics

Displaying 61–66 of 66 results

Potential for defective interfering particles (DIPS) to interrupt mammal-mosquito transmission of dengue virus

Dengue is a major mosquito-borne disease affecting 390 million people annually across 100 countries. Disease results from infection with dengue viruses, which are single positive-stranded RNA viruses in the family Flaviviridae. Defective interfering particles (DIPs) are virus-like particles with greatly reduced genomes that are byproducts of RNA virus replication and replicate only in the presence of standard virus (Vignuzzi and Lopez 2019, doi: 10.1038/s41564-019-0465-y). DIPs occur naturally during Dengue infection (Li et al. 2011, doi: 10.1371/journal.pone.0019447) and suppress DENV replication …

Study level
Master of Philosophy
Faculty
Faculty of Health
School
School of Biomedical Sciences

Can virus-based defective interfering particles (DIPS) be used to treat dengue infection?

Infection by dengue virus causes incapacitating and potentially dangerous acute disease in humans. Dengue is a mosquito-borne infectious disease with about 100 million serious clinical infections annually. Considerable effort in drug development is underway, but no effective drug therapy is available. A major difficulty for drug development is the rapid evolution of RNA viruses, like dengue virus, which presents a major challenge for controlling virus transmission and infection using conventional pharmaceuticals and vaccines.This project is based on the observation that …

Study level
Master of Philosophy
Faculty
Faculty of Health
School
School of Biomedical Sciences

Quantifying sedimentation on reefs using Google Earth Engine

Decreasing water quality is negativtly impacting coral reefs globally and is a threat that can be actively managed.

Study level
Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Earth and Atmospheric Sciences
Research centre(s)

Centre for the Environment

Antibiotic-loaded polymer nanoparticulate inhaled formulations against lung infections associated with COPD and CF

Lower respiratory tract infections (LRTIs) are one of the fatal diseases of the lungs that have severe impacts on public health especially the Indigenous people. The currently available antibiotics administered orally for the treatment of LRTIs need high doses with frequent administration and cause dose-related adverse effects.To overcome this problem, we will investigate the development of antibiotic-loaded polymer nanoparticles (NPs) for potential pulmonary delivery from dry powder inhaler (DPI) formulations. This study will address the release profile of the antibiotic …

Study level
PhD
School
School of Clinical Sciences
Research centre(s)
Centre for Materials Science
Centre for Immunology and Infection Control

Scheduling of vessel movements in channel constrained ports

International trade is heavily reliant on maritime transportation which constitutes 80% of total volume. Ports have a significant impact on the efficiency of maritime transportation, with significant delays to vessels observed in accessing or departing ports. These delays can be a result of constraints on wharf capacity, channel capacity, access to tugs and pilots, or a combination of these factors. This project will focus on the development of novel operations research techniques to optimise the efficiency of scheduling vessel movements …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Science
School
School of Mathematical Sciences
Research centre(s)
Centre for Data Science

Exploding shallow marine volcanoes: investigating the petrology of the 2019 pumice raft-producing eruption from Volcano 0403-091, Tonga

More than 21,000 km of submarine volcanoes front subduction zones, many of which lie in shallow water close to inhabited areas. Eruptions at these volcanoes can be explosive and may have significant impacts on nearby communities, or generate pumice rafts that prolong impact at remote locations. For the first time, samples of a shallow marine explosive eruption have been collected from the buoyant pumice raft and from the seafloor at the vent of Volcano 0403-091, Tonga.

Study level
PhD, Master of Philosophy
Faculty
Faculty of Science
School
School of Earth and Atmospheric Sciences
Research centre(s)
Centre for Materials Science
Centre for the Environment

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