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Found 3 matching student topics

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New antimicrobial compounds with biofouling properties

Bacteria can readily adhere to the surface of synthetic materials and form a biofilm which is much more difficult to combat than circulating bacteria due to their extreme resistance to antibiotics. Thus, biofilms are of particular concern in the healthcare system, where they increase infection rates by contaminating medical devices, delay chronic wound healing and contribute to tooth decay. In systems used to transport water and oil, biofilms are associated with pipe blockages and corrosion which can result decreased efficiencies …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Chemistry and Physics
Research centre(s)
Centre for Materials Science

A preclinical evaluation pipeline for new antivirulence drugs targeting multidrug resistant bacterial pathogens

A post-antibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century.’ - WHO, 2014 (1). Antimicrobial resistance (AMR) is a global public health priority. If no action is taken, AMR is predicted to kill more people than cancer and diabetes combined by 2050, with 10 million deaths estimated each year and a global cost of up to 100 trillion USD. New therapies to tackle multidrug …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Characterisation of emerging multidrug resistant E. coli pathogens

The last fifteen years have witnessed an unprecedented rise in the rates of antimicrobial resistance among Gram-negative bacteria, described by the World Health organisation as a global health crisis (1). Escherichia coli sequence type 131 (E. coli ST131) is a ‘high-risk’ group of Gram-negative pathogens that have emerged rapidly and spread worldwide in the period of the last 10 years (2). E. coli ST131 strains are typically resistant to multiple classes of antibiotics and cause bloodstream and urinary tract infections …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

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