QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 7 matching student topics
Displaying 1–7 of 7 results
Develop microfluidic technologies for cardiovascular and cerebrovascular diseases
The sudden rupture of vulnerable atherosclerotic plaques and subsequent thrombosis formations are responsible for most acute vascular syndromes, such as myocardial infarction and stroke. Many victims who are apparently healthy die suddenly with no prior symptoms. Such deaths could be prevented through surgery or alternative medical therapy, if vulnerable plaques were identified earlier in their natural progression.To address this pressing need, we're developing simple-to-use, high-throughput and highly-informative microfluidic biochips to understand the sequences of molecular events underlying biomechanical thrombosis (mechanobiology). …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
How do healthy people sleep? Biomechanics, physiology, and environment - what matters most?
In the Westernized world a person typically spends one third of their life in bed, with more time spent sleeping in a bed than in any other single activity. Sleep amount and quality of sleep have a direct impact on mood, behaviour, motor skills and overall quality of life. Yet, despite how important restful sleep is for the body to maintain good health, there is a comparatively small amount of studies evaluating key multi-factorial and biomechanical determinants of restful sleep …
- Study level
- PhD
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Optical coherence tomography imaging of arterial tissue
The sudden rupture of vulnerable atherosclerotic plaques and subsequent thrombosis formations are responsible for most acute vascular syndromes, such as myocardial infarction and stroke. Many victims who are apparently healthy die suddenly with no prior symptoms.Such deaths could be prevented through surgery or alternative medical therapy, if vulnerable plaques were identified earlier in their natural progression.While intravascular methods have been developed to visualize various features of vulnerable plaques, there is no single technique that can accurately predict plaque rupture in …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Develop point-of-care microfluidic technologies for cardiovascular and cerebrovascular diseases
Excessive clotting (thrombosis) leads to the cardiovascular diseases such as heart attack and stroke, killing one Australian every 12 minutes. It has long been recognized that platelets play a central role in thrombosis and are unique in their ability to form stable adhesive interactions under conditions of rapid blood flow.We've recently discovered a new ‘biomechanical’ prothrombotic mechanism that highlights the remarkable platelet sensitivity to the shear stress gradients of blood flow disturbance. Importantly, we've found that current anti-thrombotic drugs, such …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Centre for Biomedical Technologies
Image-based computational model to predict intracranial aneurysm rupture
Intracranial aneurysms are bulging, weak areas of an artery that supply blood to the brain which are relatively common. While most aneurysms do not show symptoms, 1% spontaneously rupture which can be fatal or it can leave the survivor with permanent disabilities. This catastrophic outcome has motivated surgeons to operate on approximately 30% of aneurysms despite their rate of complications arising and cost of operation.The impact of aneurysm morphology on blood flow shear stress and rupture could educate surgical decision-making …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
A new physics informed machine learning framework for structural optimisation design of the biomedical devices
The machine learning based computer modelling and simulation for engineering and science is a new era. The optimisation analysis is widely used in the design of structures.
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Centre for Biomedical Technologies
Development of bioengineered 3D tumour models for preclinical breast cancer research
3D organoid model technologies have led to the development of innovative tools for precision medicine in cancer treatment. Yet, the lack of resemblance to native tumours, and the limited ability to test drugs in a high-throughput mode, has limited translation to practice.This project will progress organoid models by using advanced tissue engineering technologies and high-throughput 3D bioprinting to recreate 'mini-tumours-in-a-dish' from a patient’s own tumour cells, and study the effects of various components of the tumour microenvironment on drug response.In …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Biomedical Technologies
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