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Found 4 matching student topics

Displaying 1–4 of 4 results

Engineering Chimeric Antigen Receptor (CAR) T cell for the treatment of cancer

Chimeric Antigen Receptor (CAR) T cells are genetically modified immune cells that can recognise and kill cancer cells. They do so through the CAR, which recognises specific antigens expressed on cancer cells. CAR T cell therapy has emerged as an effective form of cancer immunotherapy in certain types of blood cancers and are now approved for use in patients. However, CAR T cell therapy can only benefit a very small proportion of cancer patients at present because it is very …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Development of a machine learning algorithm for high throughput cell response data in drug therapy

High-throughput screening assays are essential for accelerating drug discovery, but current assays often rely on endpoint measurements that do not capture the dynamic response of cells to drug treatment. Machine learning algorithms (MLAs) have the potential to enable real-time, high-throughput monitoring of cell response to drug treatment by analyzing complex datasets generated by multiplexed live-cell assays. This research project aims to develop an MLA for enabling high throughput cell response data in drug treatment. The project will involve three main …

Study level
Honours
Faculty
Faculty of Engineering
School
School of Computer Science
Research centre(s)
Centre for Biomedical Technologies
Centre for Biomedical Technologies

Hearing colour and seeing sound – switchable optoacoustic imaging agents

Optoacoustic imaging is a relatively new medical imaging technique. It utilises laser light to excite an imaging agent, which in turn converts this light energy into heat. This heat is dissipated as a sound wave, which can be detected with an ultrasound receiver. This technique aims to overcome the minimal penetration depth of fluorescence imaging, and the lack of molecular specificity of ultrasound.In this project we are aiming to develop and synthesize intelligent imaging agents for optoacoustics, which are able …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Chemistry and Physics
Research centre(s)
Centre for Materials Science

Exploring chemotherapy-induced molecular aging and its relationship to exercise

Ovarian cancer is the sixth most common cause of death from cancer in women, with a five-year survival rate of less than 45 per cent. However, there is emerging research that shows the benefits of exercise therapy during recovery following certain cancer treatments, and how exercise can improve and extend the lives of women with ovarian cancer.This project is a collaboration exploring these health and survival outcomes in ovarian and other gynaecological cancers, and in particular how new diagnostic testing …

Study level
Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

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