QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 468 matching student topics
Displaying 109–120 of 468 results
Uncovering the dark transcriptome and proteome with long-read sequencing
Parts of the transcriptome and proteome are invisible to current technologies. We refer to them as the dark transcriptome and proteome and they encompass uncharacterised mRNA and protein isoforms. Importantly, this hidden molecular phenotype is believed to play a critical role in animal health and behavior.Recent developments in mRNA analytical methods such as long-read sequencing (PacBio, ONT) have enabled better characterization of isoforms and are redefining the transcriptome landscape in many species. We and others have found that data generated …
- Study level
- Honours
- Faculty
- Faculty of Science
- School
- School of Biology and Environmental Science
Development of a Microfluidic Gut-Brain Axis Chip
The gut microbiome refers to the collection of micro-organisms that are living symbiotically in the human or animal gastrointestinal tract (defined as the “microbiota”), their genetic material as well as the surrounding environmental habitat. It is now appreciated that the microbiome plays an important role in human health and diseases. Many neurodegenerative diseases, such as Parkinson's Disease have been linked to dysregulation of the gut microbiota. However, it is difficult to study gut-brain axis using animal models due to inter-species …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Centre for Microbiome Research
Big Data ideas for GLMs
The goal of this project is to develop new Bayesian methods for large-scale data analysis using subsampling techniques. The focus of the project will be on generalised linear models (GLMs), which are commonly used models in statistics and machine learning.One of the main challenges in using Bayesian statistics with big data is the high computational cost associated with processing big datasets. The proposed project aims to address this challenge by developing new subsampling techniques for Piecewise Deterministic Markov Process (PDMP) …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
- Research centre(s)
- Centre for Data Science
Unlocking the Potential of Simplex-Truncated Distributions
This PhD project aims to develop new methods for generating random samples from a specific type of probability distributions called simplex-truncated distributions. These distributions are commonly used in various fields such as statistics, machine learning, and biology.The project will involve the development of new techniques to generate random samples from simplex-truncated distributions. These techniques are based on a method called continuous-time Monte Carlo which is a cutting edge method in statistics that can generate random samples from complex distributions.The main …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
- Research centre(s)
- Centre for Data Science
Understanding and designing for digital self-care
The aim of this project is to better understand self-care practices with digital technologies amongst young adults and to explore opportunities for digital technology design.Self-care is a process of purposeful engagement in practices that promote holistic health and well-being of the self. Holistic health implies overall health and this encompasses more than just physical health but also includes mental, emotional and even spiritual health of a person. For some people, cooking can be a form of self-care to eat healthily …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Computer Science
Mapping the world: understanding the environment through spatio-temporal implicit representations
Accurately mapping large-scale infrastructure assets (power poles, bridges, buildings, whole suburbs and cities) is still exceptionally challenging for robots.The problem becomes even harder when we ask robots to map structures with intricate geometry or when the appearance or the structure of the environment changes over time, for example due to corrosion or construction activity.The problem difficulty is increased even more when sensor data from a range of different sensors (e.g. lidars and cameras, but also more specialised hardware such as …
- Study level
- PhD
- Faculty
- Faculty of Engineering
- School
- School of Electrical Engineering and Robotics
- Research centre(s)
- Centre for Robotics
Low-cost portable Magnetic Resonance Imaging for clinical applications
The aim of this project is to develop accurate low-cost medical imaging methodology for pseudo-3D mapping of Mammographic Density (MD) within the breast. MD is the degree of radio-opacity (“whiteness”) in an X-ray mammogram. It has implications for breast cancer risk, ease of detection of breast cancer, and monitoring of the efficacy of hormonal breast cancer prevention or anti-cancer treatments.Healthcare ChallengeThere is a growing need for affordable and accurate quantitative assessment of MD without ionising radiation. Magnetic resonance imaging (MRI) …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Chemistry and Physics
Genome to phenome: exploiting multi-omics and deep learning strategies to decipher importance of isoforms in health and behaviour
The molecular process that leads to multiple mRNA transcripts being produced from the same segment of DNA (aka gene) is known as alternative splicing (AS). This is a common form of regulation in higher eukaryotes, enabling the production of novel protein isoforms, which in turn are known to have a big impact on phenotype. Understanding the regulatory factors involved in AS, including epigenetic mechanisms such as DNA methylation, will offer key insights into important biological phenomena (health disease, behaviour, production). …
- Study level
- PhD
- Faculty
- Faculty of Science
- School
- School of Biology and Environmental Science
Preventing arterial catheter-related harm in intensive care
Each year more than 200,000 patients (adults and children) are admitted to intensive care units (ICU) in Australia and New Zealand for treatment of serious and life-threatening injury or illness, or recovery from major surgery. The vast majority (~90%) of ICU patients will require an arterial catheter during their admission to optimise vital treatment and monitoring. Arterial catheters are small hollow plastic tubes inserted into peripheral arteries to facilitate continuous haemodynamic monitoring (e.g. blood-pressure) and frequent blood sampling. Hence, effective …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Nursing
- Research centre(s)
- Centre for Healthcare Transformation
Prescriptive process analytics
With growing significance of data there is a need to harness the potential of that data for improved business operations. Historical data is often to provide a descriptive overview of how business processes have performed in the past. However, there is a need to be proactive and take appropriate actions to ensure that business processes perform in an optimal manner. Prescriptive analytics is a process that analyzes data and provides instant recommendations on how to optimize business practices. Prescriptive analytics …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Information Systems
Human biomarkers of stress, trauma, and memories of fear
Understanding how disorders such as posttraumatic stress disorder develop following trauma is a contemporary challenge for researchers in psychology. The best explanations involve a combination of psychological and biological factors that interact during and following trauma to create a range of troubling symptoms. This project will use cutting edge technology at QUT to provide insights into how a mix of biology and behaviour can result in exacerbated stress responses and threat memories in experimental and real-world settings.
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Psychology and Counselling
Genetics of cardiovascular disease
This research project involves investigating the genetic basis of cardiovascular disease (CVD). The project will focus on the genetically unique population of Norfolk Island. The Norfolk Island Health Study has been running for 20 yrs. Over this time the cardiovascular health of the Islanders has been tracked via the collection of relevant clinical data. In addition whole genome sequence data from the study group has been collected, which will facilitate the discovery of genetic variants that influence CVD phenotypes - …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
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