QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 494 matching student topics
Displaying 169–180 of 494 results
Microfluidic chip-based tumor-immune cancer models for biomarker discovery
In-vitro profiling of tumour-immune cell interactions in proximity can provide valuable insight into patient response to new combinatorial immunotherapies that are in the pipeline and currently being tested in clinical trials. These in-vitro models allow for a more controlled and isolated environment and provide a methodical approach for generating quantifiable data characterizing the interactions between target and effector cells. Traditionally executed in well-plates, tumour-immune models have been slowly moving towards a microfluidic chip-based approach for several reasons: better control over …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Unlocking the Potential of Simplex-Truncated Distributions
This PhD project aims to develop new methods for generating random samples from a specific type of probability distributions called simplex-truncated distributions. These distributions are commonly used in various fields such as statistics, machine learning, and biology.The project will involve the development of new techniques to generate random samples from simplex-truncated distributions. These techniques are based on a method called continuous-time Monte Carlo which is a cutting edge method in statistics that can generate random samples from complex distributions.The main …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
- Research centre(s)
- Centre for Data Science
Mapping the world: understanding the environment through spatio-temporal implicit representations
Accurately mapping large-scale infrastructure assets (power poles, bridges, buildings, whole suburbs and cities) is still exceptionally challenging for robots.The problem becomes even harder when we ask robots to map structures with intricate geometry or when the appearance or the structure of the environment changes over time, for example due to corrosion or construction activity.The problem difficulty is increased even more when sensor data from a range of different sensors (e.g. lidars and cameras, but also more specialised hardware such as …
- Study level
- PhD
- Faculty
- Faculty of Engineering
- School
- School of Electrical Engineering and Robotics
- Research centre(s)
- Centre for Robotics
Low-cost portable Magnetic Resonance Imaging for clinical applications
The aim of this project is to develop accurate low-cost medical imaging methodology for pseudo-3D mapping of Mammographic Density (MD) within the breast. MD is the degree of radio-opacity (“whiteness”) in an X-ray mammogram. It has implications for breast cancer risk, ease of detection of breast cancer, and monitoring of the efficacy of hormonal breast cancer prevention or anti-cancer treatments.Healthcare ChallengeThere is a growing need for affordable and accurate quantitative assessment of MD without ionising radiation. Magnetic resonance imaging (MRI) …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Chemistry and Physics
Genome to phenome: exploiting multi-omics and deep learning strategies to decipher importance of isoforms in health and behaviour
The molecular process that leads to multiple mRNA transcripts being produced from the same segment of DNA (aka gene) is known as alternative splicing (AS). This is a common form of regulation in higher eukaryotes, enabling the production of novel protein isoforms, which in turn are known to have a big impact on phenotype. Understanding the regulatory factors involved in AS, including epigenetic mechanisms such as DNA methylation, will offer key insights into important biological phenomena (health disease, behaviour, production). …
- Study level
- PhD
- Faculty
- Faculty of Science
- School
- School of Biology and Environmental Science
Preventing arterial catheter-related harm in intensive care
Each year more than 200,000 patients (adults and children) are admitted to intensive care units (ICU) in Australia and New Zealand for treatment of serious and life-threatening injury or illness, or recovery from major surgery. The vast majority (~90%) of ICU patients will require an arterial catheter during their admission to optimise vital treatment and monitoring. Arterial catheters are small hollow plastic tubes inserted into peripheral arteries to facilitate continuous haemodynamic monitoring (e.g. blood-pressure) and frequent blood sampling. Hence, effective …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Nursing
- Research centre(s)
- Centre for Healthcare Transformation
Prescriptive process analytics
With growing significance of data there is a need to harness the potential of that data for improved business operations. Historical data is often to provide a descriptive overview of how business processes have performed in the past. However, there is a need to be proactive and take appropriate actions to ensure that business processes perform in an optimal manner. Prescriptive analytics is a process that analyzes data and provides instant recommendations on how to optimize business practices. Prescriptive analytics …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Information Systems
Human biomarkers of stress, trauma, and memories of fear
Understanding how disorders such as posttraumatic stress disorder develop following trauma is a contemporary challenge for researchers in psychology. The best explanations involve a combination of psychological and biological factors that interact during and following trauma to create a range of troubling symptoms. This project will use cutting edge technology at QUT to provide insights into how a mix of biology and behaviour can result in exacerbated stress responses and threat memories in experimental and real-world settings.
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Psychology and Counselling
Genetics of cardiovascular disease
This research project involves investigating the genetic basis of cardiovascular disease (CVD). The project will focus on the genetically unique population of Norfolk Island. The Norfolk Island Health Study has been running for 20 yrs. Over this time the cardiovascular health of the Islanders has been tracked via the collection of relevant clinical data. In addition whole genome sequence data from the study group has been collected, which will facilitate the discovery of genetic variants that influence CVD phenotypes - …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
Development of a microfluidic sample processing integrated robot (micro SPIN-R)
Microfluidic devices are increasingly relied upon to address the complexity of in-vitro disease models that are intended to mimic and provide insight into in-vivo processes and reactions to novel therapies and in turn, can become powerful companion diagnostic devices essential for predicting and individual patient’s reaction to a particular treatment. However, as these microfluidic devices become more and more prominent and necessary for addressing the drug screening and disease modeling needs of the industry, we have observed a lack in …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
The benefits of custom fit compression garments on markers of performance and recovery
Cape Bionics has its foundations in the aerospace industry in the design of compression suits worn by astronauts on the international space station. The research which underpinned the design of these space suits has now been applied to sport as a means of improving performance and recovery in elite athletes.For compression garments to be effective they must fit perfectly and apply specific pressure regimes. Cape Bionics use technology from the medical and aerospace industry to provide custom fit compression garments …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Reversing Epithelial Mesenchymal Plasticity with Eribulin to Enhance Therapy Response
Epithelial mesenchymal plasticity (EMP) is a highly regulated and powerful cellular process that is fundamental in embryonic development (1), which is hijacked by cancer cells for metastatic progression and therapy resistance in epithelial cancers (2). Eribulin is a microtubule-inhibiting cancer drug discovered in sea sponges and approved for 3rd line therapy in metastatic breast cancer, which was shown to reverse epithelial mesenchymal transition (EMT) (3).We hypothesise that eribulin’s reversal of EMT will sensitise breast cancer cells to other therapies and …
- Study level
- Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
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