QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 476 matching student topics
Displaying 277–288 of 476 results
Investigating DNA repair mechanisms in aging adult stem cells
When we age the DNA repair systems of our cells become down regulated. This results in reduced DNA repair capacity, enhanced rates of mutation load and may lead to the development of chronic aging-associated diseases including osteoporosis, Alzheimer's and cancer(1). So it is no surprise that genome instability and stem cell exhaustion, which also strongly correlates with the accumulation of DNA damage, are considered hallmarks of aging(2).However, we still lack a clear understanding on how the decrease in DNA repair …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Investigation of genetic factors that contribute to concussion and its outcomes
The health outcomes from traumatic brain injuries (TBIs) and concussion depend on the nature of the injury, but response also varies greatly between individuals, suggesting that genetic factors may play a role. In particular, due to effects of head trauma on balances of ions, neurotransmitters and energy use in the brain, there is suggestion that variation in the genes that encode proteins involved in these pathways, e.g. ion channels, may affect the risk of, as well as response to a …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Digital business models
The ongoing proliferation of a digital lifestyle and the exposure to global innovation raises the expectation level of customers for new products and services. The ongoing technological innovations make this possible, but require digital business models to turn them into viable commercial offerings.This is not only relevant for new (‘born-on-the-web’) companies, but also for traditional companies who run the risk of having their core business disrupted. While some struggle with the new business models (e.g. Kodak), others turn it into …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Information Systems
- Research centre(s)
- Centre for Future Enterprise
Business model innovation
Business models are becoming an important focus of innovation activities of practitioners and innovation studies of academics.When organisations want to introduce new products or services or need to transform their existing products or services, a viable business model is a critical requirement for commercial success. For example, many internet services are provided for free and require providers to find alternative sources of revenue, such as advertisements or premium services.In addition, the innovation of the business model itself is often a …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Information Systems
- Research centre(s)
- Centre for Future Enterprise
Multi-microbial 3D printing for screening microbiome functions
The ability to 3D print bacteria has relevance to a wide range of applications, ranging from developing novel anti-microbial modalities to probiotics for promoting human health. Traditional culture techniques used in microbiology such as agar plates and suspension cultures have limited spatio-temporal control over the bacteria microenvironment as well as their interaction partners, in particular, mammalian host cells. This project aims to bridge this technological gap by combining 3D printing and microfluidics technologies to spatially control the localisation of multiple …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
An airway chip for screening viral infection mediated immune responses
Respiratory infections such as influenza, SARS-COV-2, COVID-19, and MERS are increasingly prevalent. Complications and related deaths arising from these infections are often the result of a “cytokine storm”, whereby there is an over production of proinflammatory soluble factors by immune cells, which dictates symptoms severity and mortality risk. Recent works showed that immunomodulatory therapy, with or without antiviral agents, may improve recovery outcome. However, the screening of suitable immune-modulatory and antiviral agents relies heavily on animal models which can't capture …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
Molecular simulation of rotational diffusion in ideal liquids
Rotational tumbling of molecules in a liquid is an important phenomenon in Magnetic Resonance Imaging (MRI) because it determines the spin-relaxation rates of the resident nuclei which can determine MRI contrast.For a relatively simple molecular process, the theoretical description of rotational motion of molecules in liquids remains controversial. The most commonly used model, the Debye model, assumes that:the rotational diffusion propagator of a tumbling molecule is a solution of the diffusion equation on a spherical surfacethis solution is described by …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Chemistry and Physics
- Research centre(s)
- Centre for Materials Science
Haptics controllers for natural interactions in VR
Virtual reality (VR) technologies have become cheaper and more accessible in the last couple of years. This allowed for exploring their use in different areas including gaming, health, education and training settings.While VR can provide high immersion via augmenting our senses in the virtual environment, user interaction with the virtual environment has been limited relying on pre-set gestures or default controllers designed by the companies who built the VR gears.The Vive Tracker is an accessory for HTC Vive which allows …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Computer Science
Cultural Legalities of Social Media and Mobile Digital Devices in the Global South
Mobile digital technologies and with them digital platforms have had dramatic exponential growth within the Global South since 2015. In so doing the digital is disrupting and transforming traditional, colonial and post-colonial cultural and legal orders. This project focuses on the cultural transformation, and legal reactions, to social media and the proliferation of mobile digital devices in Global South communities. Joining an innovative intellectual community with existing projects on issues of technology and digital justice in the Global South, candidates …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Business and Law
- School
- School of Law
- Research centre(s)
- Centre for Justice
Human-in-the-loop techniques to debug machine learning models
Machine learning models are being deployed in critical domains such as healthcare, education and fintech. The current approach to deploying machine learning models is based on considering a data-centric approach where the models are evaluated using performance measures on a test set. However, the high performance of the model on test data is not indicative of its reliability,An important aspect of reliability is in the understanding of what exactly a machine learning model encodes, and to verify if it learns …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Information Systems
Tailoring 2D materials via interface engineering
2D materials are crystalline materials with only a single layer thickness. The best known 2D materials is graphene, but it also encompasses a large family of materials , such as transition metal dichalcogenides (TMDCs).2D materials are set for breakthroughs in fundamental research and transformative technologies. They have few surface dangling bonds and unique atomic-level uniformity which make them very appealing for developing optical, electronic and energy applications.These materials also bring a new degree of freedom to combine highly distinct materials, …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Chemistry and Physics
- Research centre(s)
- Centre for Materials Science
Renewal and differentiation in human neural stem cells and their application to understanding neurological disorders
The effective regeneration of brain tissue requires an understanding of the factors mediating the damage as well as the integration of new/replacement cells to form new functional neural networks. The isolation and expansion of human stem cells and limited neural lineage differentiation have provided the foundation for strategies in the treatment of neurodegenerative disorders. We utilise iPSC-derived NPCs and patient-derived (Alzheimer’s disease; AD) iPSCs and neural lineage differentiation of hMSCs, iPSC NPCs and AD iPSCs in neuronal and glial culture …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
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