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Found 3 matching student topics

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Surrogate models for accurate prediction and inference in mathematical biology

High fidelity mathematical models of biological phenomena are often complex and can require long computational runtimes which can make computational inference for parameter estimation intractable.  In this project we will overcome this challenge by working with computationally simple low fidelity models and build a simple statistical model of the discrepancy between the high and low fidelity models.  This approach provides the best of both worlds: we obtain high accuracy predictions using a computationally cheap model surrogate.

Study level
PhD, Master of Philosophy
Faculty
Faculty of Science
School
School of Mathematical Sciences
Research centre(s)
Centre for Data Science

Branching processes, stochastic simulations and travelling waves

Branching processes are stochastic mathematical models used to study a range of biological processes, including tissue growth and disease transmission.This project will implement a simple stochastic branching process to generate simulations of biological growth, and then consider differential equation-based description of the stochastic model.Using computation we will compare the two models, and use phase plane and perturbation analysis to analyze the resulting traveling wave solutions.

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Mathematical Sciences
Research centre(s)
Centre for Data Science

Moving boundary problems in mathematical biology

Invasion of biological cells or ecological populations involves moving fronts that invade into previously unoccupied regions of space. Such moving fronts are driven by a combination of motility, such as random diffusion, and proliferation, such as logistic growth. Understanding how best to model such invasive fronts is important as moving fronts of cells are associated with wound healing and cancer progression and moving fronts in ecology are associated with the spreading of weeds and invasive species.Previously both continuum and discrete …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Mathematical Sciences

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