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Found 3 matching student topics

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Advanced materials for redox flow batteries

Grid-scale energy storage for intermittent renewables like solar and wind is an essential element of the transition away from fossil fuel based electricity production. Redox flow batteries have some very interesting characteristics for this stationary storage application:they are safer than other battery typesthe amount of energy stored can typically be scaled up easilythe power and energy of a system are more decoupled compared to lithium and other batteries, making them flexible in their design parameters.Ion exchange membrane and electrode are …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Chemistry and Physics
Research centre(s)
Centre for Materials Science

Identification of novel melanoma biomarkers using exosomes

Tumour cells excrete exosomes, membrane vesicles (30-150 nm diameter) that encapsulate and transport proteins, metabolites and genetic material. They mediate intercellular communication within the tumor microenvironment, metastasis formation via circulation, and development of drug resistance. Circulating tumor-derived exosomes can be isolated from blood patients as a non-invasive liquid biopsy.The chemical composition and overall properties of the exosomal membranes are expected to be similar to those of parent cell membranes and to modulate blood circulation time, and uptake and targeting of …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Characterisation of melanoma cell membranes to identify novel drug targets

Cell membrane structure and function are altered during tumour development, but to date comprehensive studies on the characterisation of cell membranes of a given cancer are scarce, or are only focused on a particular property (e.g. overall charge, global lipid composition, or specific lipid). In preliminary work we compared the lipidome (i.e. the lipid profile) of a panel of cells, and found the lipid composition of model melanoma cells to be distinct from that of other cancerous and non-cancerous cells. …

Study level
PhD
Faculty
Faculty of Health
School
School of Biomedical Sciences

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