QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 4 matching student topics
Displaying 1–4 of 4 results
Uncovering the dark transcriptome and proteome with long-read sequencing
Parts of the transcriptome and proteome are invisible to current technologies. We refer to them as the dark transcriptome and proteome and they encompass uncharacterised mRNA and protein isoforms. Importantly, this hidden molecular phenotype is believed to play a critical role in animal health and behavior.Recent developments in mRNA analytical methods such as long-read sequencing (PacBio, ONT) have enabled better characterization of isoforms and are redefining the transcriptome landscape in many species. We and others have found that data generated …
- Study level
- Honours
- Faculty
- Faculty of Science
- School
- School of Biology and Environmental Science
Genome to phenome: exploiting multi-omics and deep learning strategies to decipher importance of isoforms in health and behaviour
The molecular process that leads to multiple mRNA transcripts being produced from the same segment of DNA (aka gene) is known as alternative splicing (AS). This is a common form of regulation in higher eukaryotes, enabling the production of novel protein isoforms, which in turn are known to have a big impact on phenotype. Understanding the regulatory factors involved in AS, including epigenetic mechanisms such as DNA methylation, will offer key insights into important biological phenomena (health disease, behaviour, production). …
- Study level
- PhD
- Faculty
- Faculty of Science
- School
- School of Biology and Environmental Science
The role of genetics in the development and mechanism of human traits
The Statistical and Genomic Epidemiology Laboratory (SGEL) studies the role of genetics in the development and mechanism of human traits, with particular emphasis on migraine, and the specific goal of identifying genetic risk factors and detecting common genetic links with other disorders, in particular depression, endometriosis, and epilepsy.
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
Multi-microbial 3D printing for screening microbiome functions
The ability to 3D print bacteria has relevance to a wide range of applications, ranging from developing novel anti-microbial modalities to probiotics for promoting human health. Traditional culture techniques used in microbiology such as agar plates and suspension cultures have limited spatio-temporal control over the bacteria microenvironment as well as their interaction partners, in particular, mammalian host cells. This project aims to bridge this technological gap by combining 3D printing and microfluidics technologies to spatially control the localisation of multiple …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
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