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Found 3 matching student topics

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Topics in computational Bayesian statistics

Bayesian statistics provide a framework for a statistical inference for quantifying the uncertainty of unknowns based on information pre and post data collection.This information is captured in the posterior distribution, which is a probability distribution over the space of unknowns given the observed data.The ability to make inferences based on the posterior essentially amounts to efficiently simulating from the posterior distribution, which can generally not be done perfectly in practice.This task of sampling may be challenging for various reasons:The posterior …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Mathematical Sciences
Research centre(s)
Centre for Data Science

Efficient parameter estimation for agent-based models of tumour growth

Cancer is an extremely heterogeneous disease, particularly at the cellular level. Cells within a single cancerous tumour undergo vastly different rates of proliferation based on their location and specific genetic mutations. Capturing this stochasticity in cell behaviour and its effect on tumour growth is challenging with a deterministic system, e.g. ordinary differential equations, however, is possible with an agent-based model (ABM). In an ABM, cells are modelled as individual agents that have a probability of proliferation and movement in each …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Mathematical Sciences
Research centre(s)
Centre for Data Science

Efficient Parameter Estimation for Stochastic Simulations

Stochastic simulation-based models are routinely used in many areas of science to describe inherent randomness in many real-world systems. Applications include the study of particle physics, imaging if black holes, biochemical processes, the migration of animals, and the spread of infectious diseases. To apply these models to interpret data requires statistical methods to estimate model parameters.Unfortunately, standard statistical techniques are not capable of analysing data using these models. This is largely due to the model likelihood, the probability of the …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Mathematical Sciences
Research centre(s)
Centre for Data Science

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