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Found 5 matching student topics

Displaying 1–5 of 5 results

Polymer particles as precision sensors for molecules

Polymer particles are a billion-dollar industry with a diverse range of applications from biomedical to industrial coatings. As a prime example, point-of-care testing devices rely on polymeric particles with various size and functionality to conveniently allow instantaneous, selective, and precise diagnostics. However, as new applications arise and current applications advance, these demand the preparation of increasingly complex material and particle systems.The Soft Matter Materials Team has developed a simple method to form uniform particles without any additives, initiators or stabilizers. …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Chemistry and Physics
Research centre(s)
Centre for Materials Science

Separating nonlinear optical effects in optical limiters

Optical limiting uses a medium’s nonlinear response to allow light at low intensities to be transmitted, but restricts transmission at high intensities so as to safeguard sensitive detectors including the eye. A popular nonlinear process used in optical limiters is two photon absorption where two high intensity light photons are simultaneously absorbed thereby reducing the light transmission through the medium. Unfortunately, in gold nanoparticle optical limiters a second nonlinear process can arise – saturated absorption which leads to an increase …

Study level
Honours
Faculty
Faculty of Science
School
School of Chemistry and Physics
Research centre(s)
Centre for Materials Science

Design, derivation, and implementation of mesh-free finite volume solvers based on 3D unit cell morphology to estimate biomass particle effective parameters

The aim of this PhD project is to use lignocellulosic morphological features extracted from high resolution micro-CT images of biomass particles undergoing a dilute acid pretreatment process to perform computational homogenisation over representative unit cell configurations. Mesh-free finite volume solvers will be developed based on 3D point cloud data sets to estimate virtual biomass particle effective parameters, such as diffusivity, thermal conductivity, and permeability. The simulation results will be analysed to provide a fundamental understanding of the impact that changes …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Mathematical Sciences

Potential for defective interfering particles (DIPS) to interrupt mammal-mosquito transmission of dengue virus

Dengue is a major mosquito-borne disease affecting 390 million people annually across 100 countries. Disease results from infection with dengue viruses, which are single positive-stranded RNA viruses in the family Flaviviridae. Defective interfering particles (DIPs) are virus-like particles with greatly reduced genomes that are byproducts of RNA virus replication and replicate only in the presence of standard virus (Vignuzzi and Lopez 2019, doi: 10.1038/s41564-019-0465-y). DIPs occur naturally during Dengue infection (Li et al. 2011, doi: 10.1371/journal.pone.0019447) and suppress DENV replication …

Study level
Master of Philosophy
Faculty
Faculty of Health
School
School of Biomedical Sciences

Can virus-based defective interfering particles (DIPS) be used to treat dengue infection?

Infection by dengue virus causes incapacitating and potentially dangerous acute disease in humans. Dengue is a mosquito-borne infectious disease with about 100 million serious clinical infections annually. Considerable effort in drug development is underway, but no effective drug therapy is available. A major difficulty for drug development is the rapid evolution of RNA viruses, like dengue virus, which presents a major challenge for controlling virus transmission and infection using conventional pharmaceuticals and vaccines.This project is based on the observation that …

Study level
Master of Philosophy
Faculty
Faculty of Health
School
School of Biomedical Sciences

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