QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 293 matching student topics
Displaying 217–228 of 293 results
Post-translational modification of proteins in cancer
The Protein Ablation Cancer Therapeutics (PACT) laboratory are interested in understanding how post-translational modifications contribute to the tumorigenic functions of proteins in cancer cells. We hypothesise that particular post-translational modifications are required for the cancer-associated function of a protein and that prevention of these would be a useful approach to treating cancer.The aim of this project is to select a candidate protein from our database of potential targets, confirm the protein is modified, identify the key modified lysine in the …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Develop microfluidic technologies for cardiovascular and cerebrovascular diseases
The sudden rupture of vulnerable atherosclerotic plaques and subsequent thrombosis formations are responsible for most acute vascular syndromes, such as myocardial infarction and stroke. Many victims who are apparently healthy die suddenly with no prior symptoms. Such deaths could be prevented through surgery or alternative medical therapy, if vulnerable plaques were identified earlier in their natural progression.To address this pressing need, we're developing simple-to-use, high-throughput and highly-informative microfluidic biochips to understand the sequences of molecular events underlying biomechanical thrombosis (mechanobiology). …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Human robotic interaction prototyping toolkit
Design relies on prototyping methods to help envisage future design concepts and elicit feedback from potential users. A key challenge the design of human-robot interaction (HRI) with collaborative robots is the current lack of prototyping tools, techniques, and materials. Without good prototyping tools, it is difficult to move beyond existing solutions and develop new ways of interacting with robots that make them more accessible and easier for people to use.This project will develop a robot collaboration prototyping toolkit that combines …
- Study level
- PhD
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
-
Design Lab
Robotic intention visualisation
Complex manufacturing environments characterised by high value and high product mix manufacturing processes pose challenges to Human-Robot Collaboration (HRC). Allowing people to see what robots are ‘thinking’ will allow workers to efficiently collaborate with co-located robotic partners. A tighter integration of work routines requires improved approaches to support awareness in human-robotic co-working spaces. There is a need for solutions that also let people see what the robot is intending to do so that they can also efficiently adjust their actions …
- Study level
- PhD
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
-
Design Lab
Potential for defective interfering particles (DIPS) to interrupt mammal-mosquito transmission of dengue virus
Dengue is a major mosquito-borne disease affecting 390 million people annually across 100 countries. Disease results from infection with dengue viruses, which are single positive-stranded RNA viruses in the family Flaviviridae. Defective interfering particles (DIPs) are virus-like particles with greatly reduced genomes that are byproducts of RNA virus replication and replicate only in the presence of standard virus (Vignuzzi and Lopez 2019, doi: 10.1038/s41564-019-0465-y). DIPs occur naturally during Dengue infection (Li et al. 2011, doi: 10.1371/journal.pone.0019447) and suppress DENV replication …
- Study level
- Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Therapeutic opportunities targeting epigenetic-metabolism crosswalks in cancer
Epigenetic and metabolic pathways in cancer cells are highly interconnected. Epigenetic landscape in cancer cells is modified by oncogene-driven metabolic changes. Metabolites modulate the activities of epigenetic modifying enzymes to regulate the expression of specific genes. Conversely, epigenetic deregulation that occurs in cancer affect the expression of metabolic genes, thereby altering the metabolome. These changes all coordinately enhance cancer cell proliferation, metastasis and therapy resistance.The overall aim of the project is to understand the link between the activity of epigenetic …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Computational drug repurposing for neuropsychiatric disease
While hundreds of robust genetic associations have been found for neuropsychiatric disease (such as schizophrenia, major depression, and anxiety) understanding the exact molecular mechanisms leading to disease onset and progression remains challenging. Inherited (i.e. genetic) risk factors for many neuropsychiatric diseases converge on genes that are co-ordinately expressed (co-expressed) in a disease-relevant tissue (e.g. brain). The study of how genetic risk factors affect co-expressed genes (i.e. gene co-expression analysis) has the potential to uncover new biological processes underlying disease onset. …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Spatial localisation of immunoglobulin A in the gastrointestinal tract.
Blood cancers, which include leukaemia, lymphoma and myeloma account for 10% of all cancers and 9.4% of cancer deaths. Stem cell transplantation (SCT) is the predominant curative therapy for these diseases. However, a major complication is graft-versus-host disease (GVHD) in which the gastrointestinal (GI) tract, skin, lung and liver are preferentially damaged by the transplanted donor immune system, limiting the therapeutic potential of this treatment. Thus, there is a pressing need for new treatment approaches to improve transplant outcome for …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
The interplay between environmental and genetic risk factors in the etiology of mental health disorders
Mental health disorders (e.g., depression, anxiety, substance use) are the leading cause of global disease burden in the young adult population. Twin and family studies show that both genetic and environmental factors play a large role in the aetiology of these disorders. The Translational Neurogenomics group aims to identify genetic risk factors for a range of mental health and substance use disorders, and investigate the interplay between genetic and environmental risk factors.UK Biobank is a major national and international health …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
Giant viruses in the human gut microbiome
The human body is home to a vast ecosystem of microorganisms including bacteria, archaea, fungi, viruses, and bacteriophages that make up the human microbiota. These microbes and their collective genetic material, known as the microbiome, influence a wide range of physiological functions including nutrient production and absorption, the development and regulation of our immune system, protection against potential pathogens, and even our mood and mental health. While distinct microbial communities exist throughout the body, the gut microbiome has gained particular …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
-
Centre for Microbiome Research
3D Bioprinting in Cancer Research
Interested in 3D Bioprinting? Care about improving our understanding of cancer pathogenesis? Then this opportunity is for you! The Queensland University of Technology (QUT) and industry partner Gelomics Pty Ltd are seeking competitive candidates to apply for a PhD scholarship (AU $34,013 per annum) in 3D Bioprinting & Cancer Research.
- Study level
- PhD
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
Legal, multidisciplinary and public health research regarding child abuse and neglect
Professor Ben Mathews is an internationally recognised expert in multiple legal areas connected with child abuse and neglect. These include sexual abuse generally, physical abuse and corporal punishment, domestic violence, civil claims for child abuse, statutes of limitation, mandatory reporting laws, institutional child abuse, child protection systems, criminal prosecution, prevention, regulation and oversight, public health and public health law analyses, and children's rights. Ben welcomes all enquiries about topics connected with these themes.In addition, he is currently leading the Australian …
- Study level
- PhD
- Faculty
- Faculty of Business and Law
- School
- School of Law
- Research centre(s)
-
Australian Centre for Health Law Research
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