QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 175 matching student topics
Displaying 121–132 of 175 results
Identifying emergent ecosystem responses through genes-to-ecosystems integration at Stordalen Mire
Permafrost thaw induced by climate change is predicted to make up to 174 Pg of near-surface carbon (less than 3m below the surface) available for microbial degradation by 2100. Despite having major implications for human health, prediction of the magnitude of carbon loss as carbon dioxide (CO2) or methane (CH4) is hampered by our limited knowledge of microbial metabolism of organic matter in these environments.Genome-centric meta-omic analysis of microbial communities provides the necessary information to examine how specific lineages transform …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
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Centre for Microbiome Research
Spatial localisation of immunoglobulin A in the gastrointestinal tract.
Blood cancers, which include leukaemia, lymphoma and myeloma account for 10% of all cancers and 9.4% of cancer deaths. Stem cell transplantation (SCT) is the predominant curative therapy for these diseases. However, a major complication is graft-versus-host disease (GVHD) in which the gastrointestinal (GI) tract, skin, lung and liver are preferentially damaged by the transplanted donor immune system, limiting the therapeutic potential of this treatment. Thus, there is a pressing need for new treatment approaches to improve transplant outcome for …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Providing legal evidence for non-accidental scald burn injury
Although most burn injuries are completely accidental in nature, they can also occur due to neglect or abuse. Burn clinicians are often required to ascertain if the patient history and the wound are consistent with accidental or non-accidental injury. If the case goes to court, the clinician will prepare a medico-legal report as evidence. We have previously conducted studies examining the depth of burn injury after different durations and temperatures of hot water. This data can be used to predict …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Identifying protein and metabolite markers of burn injury and trauma
It can be difficult for clinical teams to determine the severity of burn injuries when the patient first presents to the hospital. This is because burn wounds continue to deepen/progress over time, in a process known as burn wound conversion. Some wounds may deepen over days or weeks and require aggressive surgical treatment e.g. grafting, and some wounds don’t progress, stay superficial in depth, and they can be managed conservatively with the application of different bandages or dressings. We have …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Characterisation of emerging multidrug resistant E. coli pathogens
The last fifteen years have witnessed an unprecedented rise in the rates of antimicrobial resistance among Gram-negative bacteria, described by the World Health organisation as a global health crisis (1). Escherichia coli sequence type 131 (E. coli ST131) is a ‘high-risk’ group of Gram-negative pathogens that have emerged rapidly and spread worldwide in the period of the last 10 years (2). E. coli ST131 strains are typically resistant to multiple classes of antibiotics and cause bloodstream and urinary tract infections …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
A preclinical evaluation pipeline for new antivirulence drugs targeting multidrug resistant bacterial pathogens
A post-antibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century.’ - WHO, 2014 (1). Antimicrobial resistance (AMR) is a global public health priority. If no action is taken, AMR is predicted to kill more people than cancer and diabetes combined by 2050, with 10 million deaths estimated each year and a global cost of up to 100 trillion USD. New therapies to tackle multidrug …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Degradation-conscious charging of lithium-ion batteries
The adoption of electric vehicles and grid storage systems by the present day consumers has been phenomenal. The most critical issue with the lithium-ion (Li-ion) battery is how to manage its degradation.Understanding battery degradation mechanisms and the development of charging strategies to optimally manage battery degradation is very important. There are a number of important issues that need to be addressed carefully, such as thermo-electrochemical modelling of large battery packs and fast charging protocols.
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Electrical Engineering and Robotics
Dynamic wireless transfer systems
There's a growing interest by many governments and industry sectors on dynamic wireless power transfer systems for electric vehicle charging. This means there's increased research intensity in this domain. However, there are numerous important issues that need to be addressed carefully, such as:load estimationsensorless vehicle position estimationrobust controlimproved power converter topologies.
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Electrical Engineering and Robotics
Using a natural β-carboline dimer compound to target metabolic vulnerabilities linked to glycolysis in prostate cancer
Prostate cancer is an androgen dependent cancer and treatments are aimed at preventing activation of the androgen receptor. Part of the development of resistance to therapies involves prostate cancers reprogramming their metabolism to overcome metabolic stress induced by these therapies and support growth and survival. This reprogramming involves increases in the rate of glycolysis and intermediate pathways branching from glycolysis. Previously in our laboratory, the natural compound, beta-carboline dimer, BD, was identified to have potent effects on cell viability, cell …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Moving boundary problems in mathematical biology
Invasion of biological cells or ecological populations involves moving fronts that invade into previously unoccupied regions of space. Such moving fronts are driven by a combination of motility, such as random diffusion, and proliferation, such as logistic growth. Understanding how best to model such invasive fronts is important as moving fronts of cells are associated with wound healing and cancer progression and moving fronts in ecology are associated with the spreading of weeds and invasive species.Previously both continuum and discrete …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
Understanding the immunological mechanisms that regulate increased susceptibility to respiratory syncytial viral infection after stem cell transplantation
Allogeneic stem cell transplantation (alloSCT) is considered the gold standard procedure for the treatment of blood cancers. Globally, over 9000 patients per year undergo this high-risk, life-saving therapy. However, major complications limit the therapeutic potential of this treatment which include graft-versus-host disease (GVHD) and infections due to the severe immunosuppression in these patients. Respiratory syncytial viral (RSV) infection is frequent in these patients, is often fatal and clearly a significant clinical problem. Thus, there is a pressing need for new …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
The interplay between environmental and genetic risk factors in the etiology of mental health disorders
Mental health disorders (e.g., depression, anxiety, substance use) are the leading cause of global disease burden in the young adult population. Twin and family studies show that both genetic and environmental factors play a large role in the aetiology of these disorders. The Translational Neurogenomics group aims to identify genetic risk factors for a range of mental health and substance use disorders, and investigate the interplay between genetic and environmental risk factors.UK Biobank is a major national and international health …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
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