QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 680 matching student topics
Displaying 265–276 of 680 results
The impact of neuroretinal disease on circadian behavior and sleep
Chronic sleep disruption impacts on quality of life and can lead to cardiovascular disease and cancer (Cable et al, Ann N Y Acad Sci 2021). Importantly in people with underlying chronic health conditions, circadian disruption can exacerbate symptoms, disease severity and cause disease progression.Light signalled by photoreceptors in the retina is the most important cue for setting sleep/wake cycles. The impairment of this light signalling in eye and neurodegenerative disease leads to circadian and sleep disruption (Feigl & Zele, Optom …
- Study level
- Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
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Centre for Vision and Eye Research
Exploring how entrepreneurs use social media to influence users' emotions and achieve virality
Social media has become an integral part of our lives – we click, like and share posts with our personal and professional networks each day. The concept of sharing is activated by psychological stimulation, be it emotional or physical (Tellis et al., 2019). But why are certain types of online content more viral than others?Achieving ‘virality’ is not random and isn’t just about creating engaging content. Instead there are mechanics that are planned to achieve this type of ‘social currency’. …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Business and Law
- School
- School of Advertising, Marketing and Public Relations
- Research centre(s)
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Australian Centre for Entrepreneurship Research
Prostate cancer transcriptomics (Honours and Master of Philosophy)
At the Australian Prostate Cancer Research Centre QLD, we are interested in the cellular adaptive response processes leading to therapy resistance in advanced prostate cancer.A focus area of our research is studying the transcriptome changes in prostate cancer cell lines, xenograft models and patient samples using RNA sequencing technologies.By integrating our large in-house repository of RNAseq data sets with publicly available studies, this project will further explore the cellular heterogeneity of prostate tumours and the plasticity of cancer cells in …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Using machine learning to understand how the world’s microbiomes are changing due to climate
Shotgun metagenomic sequencing has become commonplace when studying microbial communities and their relationship with the health of our planet, and their direct effects on our own health. Currently, there are >180,000 shotgun metagenomes publicly available, but until recently trying to treat these data as a resource has been challenging due to its extreme size (>700 trillion base pairs).Recently we have developed a tool that can efficiently convert this base pair information into a straightforward assessment of which microorganisms are present …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
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Centre for Microbiome Research
Characterising a DNA repair protein as an anti-cancer therapeutic target and diagnostic marker in brain cancer
Cancer is the single biggest clinical problem facing the world and will account for half of all global deaths by 2030. Even though there have been significant advances in immunotherapy, we are still unable to cure most cancers. New therapeutic targets, individualised to patient needs, must be identified and validated in order to improve cancer outcomes.Brain cancer causes more deaths in people under the age of 40 than any other cancer and more deaths in children than any other disease. …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
Post-translational modification of proteins in cancer
The Protein Ablation Cancer Therapeutics (PACT) laboratory are interested in understanding how post-translational modifications contribute to the tumorigenic functions of proteins in cancer cells. We hypothesise that particular post-translational modifications are required for the cancer-associated function of a protein and that prevention of these would be a useful approach to treating cancer.The aim of this project is to select a candidate protein from our database of potential targets, confirm the protein is modified, identify the key modified lysine in the …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
“No vaccine = no service” – Investigating consumer reactions of service exclusion
A growing number of countries in Europe have introduced a ‘hospitality green pass’ (EU Digital COVID Certificate) which is a paper document or app that proves the holder has been fully vaccinated or recovered from COVID-19. It grants consumers access to indoor restaurants, bars, cafes and other indoor venues. That is, without proof of a COVID-19 vaccination, consumers will be prohibited to enter these indoor areas.However, the introduction of green passes has also led to some backlash. For instance, some …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Business and Law
- School
- School of Advertising, Marketing and Public Relations
Improving human health through the microbiome
Every person harbours a unique collection of microorganisms - the majority of which reside in the gastrointestinal tract - that influences nearly every aspect of human health. As such, the gut microbiome is emerging as a potential tool for the diagnosis and treatment of a wide range of diseases.However, microbiome studies yield vast amounts of data, and the complexity of the microbiome makes it difficult to decipher interactions between microorganisms, host cells and environmental factors.
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
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Centre for Microbiome Research
Plasmonic metal application
Developing “light controllable product selectivity switches” is of great interest in cross-coupling reactions based chemical synthesis. On an environmentally friendly plasmonic metal nano-particle surface, light irradiation can change the reactants adsorption on the surface, and thus change the relative ratio of the reactants for reaction. Different wavelengths contribute to tune this selectivity more accurately in a molecular level.
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Chemistry and Physics
- Research centre(s)
- Centre for Materials Science
Biological and clinical impact of the association of germline variations in KLK3 (PSA) gene in prostate cancer
Prostate cancer is the most frequently occurring cancer (after skin cancers) in Australian males, and the second most common cause of cancer death. While the 5-year survival rate for localised disease approaches 100%, extra-prostatic invasion results in a poorer prognosis. Kallikreins are serine proteases, which are part of an enzymatic cascade pathway activated in prostate cancer (Lawrence et al 2010). The most well-known member is prostate specific antigen (PSA) or the KLK3 protein, encoded by the Kallikrein 3 (KLK3) gene, …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Understanding capsular polysaccharide diversity is key to next generation therapies for multi-drug resistant Acinetobacter baumannii infections
Bacteriophage therapy is an attractive innovative treatment for infections caused by extensively drug resistant Acinetobacter baumannii, for which there are few effective antibiotic treatments remaining.Capsular polysaccharide (CPS) is a primary receptor for lytic bacteriophage, thus knowledge of the chemical structures of CPS produced by the species underpins the identification of suitable phage for therapeutic cocktails.As many phage depolymerases cleave a specific CPS linkage formed by either a glycosyltransferase or polymerase enzyme, characterisation of these proteins are essential.However, these remain largely …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
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Centre for Immunology and Infection Control
Small business resilience in times of economic uncertainty: Examining retailers and regional businesses
Regional Australia is undergoing significant structural, economic, social, and environmental change which is impacting the viability of small businesses (Regional Australia Institute, 2018). Regional small retail businesses, estimated to contribute $21.9bn to local economies (Australian Small Business and Family Enterprise Ombudsman, 2019) are particularly susceptible to economic shocks, have lower survival rates, more volatile revenues and are generally less resilient than larger business (Barraket, Eversole, Luke & Barth, 2019).Disruptive external events such as the acceleration of e-retailing, COVID-19 travel restrictions, …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Business and Law
- School
- School of Advertising, Marketing and Public Relations
- Research centre(s)
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Australian Centre for Entrepreneurship Research
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