QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 662 matching student topics
Displaying 385–396 of 662 results
Light, circadian rhythms and Parkinson’s disease
Up to 98% of patients with Parkinson’s Disease (PD) have non-motor symptoms (Poewe et al. Nature Rev Dis 2017, 3: 17013) and of those, circadian and sleep disorders are the most common (for review, Gros & Videnovic. 2020, Clin Geriatr Med 36: 119). These symptoms become increasingly prevalent during the course of PD and are key determinants affecting quality of life, advancement of overall disability and placement in nursing homes (Shapira et al. Nat Rev Neurosci 2017,18:435). Circadian and sleep …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Determining the response to PARP inhibitor treatment of ovarian cancer in mouse xenograft model
Our cellular DNA is constantly under threat from both exogenous and endogenous factors. DNA repair pathways function to maintain genomic stability, preventing deleterious mutations that may ultimately lead to cancer initiation. When a tumour forms, it becomes genetically unstable, allowing environmental adaptation. This genetic instability can also result in gene mutations and protein expression alterations that can be targeted to induce cancer-specific cell death (phenomenon also known as synthetic lethality). For example, it has been shown that cells deficient in …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Characterise a novel DNA repair protein as a target for cancer therapies
Data generated in the lab has identified a novel DNA repair protein previously described as a key protein in HSP70/90 complexes. Many pathways of tumourigenesis are mediated by Heat Shock Proteins and HSP70/90 are found significantly upregulated in ovarian cancers. The targeting of HSP70/90 are an emerging therapeutic avenue for the treatment of ovarian cancer. Supporting this, an inhibitor of HSP90 has been shown to sensitise breast cancer cells to PARP inhibitors and paclitaxel.Our preliminary data indicates that this new …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Characterising the role of PARPs in DNA repair and cancer therapy
The genome of our cells is damaged multiple times each day, by various factors including sunlight and reactive oxygen species. In order for the DNA damage response to be efficient, our cells utilise highly coordinated repair pathways that function accurately and rapidly throughout the damaged cell. Cells that do not repair DNA damage correctly will accumulate damage and display increased genomic instability, which is a key hallmark of cancer cells, promoting their survival and rapid growth. DNA repair pathways are …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Restoring adiponectin signalling to prevent prostate cancer progression
Advanced prostate cancer (PCa) is a leading cause of cancer-associated death in Australian men. Anti-androgens, which exploit the tumour’s reliance on androgens for its growth and spread, offer temporary remission in advanced PCa patients, but due to treatment resistance, fail to be curative. A further complication of anti-androgens is that they trigger a deleterious suite of metabolic side-effects resembling obesity/Metabolic syndrome. These symptoms not only impact patient health but promote the tumour to be more aggressive and resist treatment. Vital …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Targeting leptin's signalling axis to prevent treatment resistance in prostate cancer
Advanced prostate cancer (PCa) is a leading cause of cancer-associated death in Australian men. Anti-androgens, which exploit the tumour’s reliance on androgens for its growth & spread, offer temporary remission in advanced PCa patients, but due to treatment resistance, fail to be curative. A further complication of anti-androgens is that they trigger a deleterious suite of metabolic side-effects resembling obesity/Metabolic syndrome. These symptoms not only impact patient health but promote tumours to be more aggressive & resist treatment. Vital new …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Modeling roost selection by flying foxes in Moreton Baty region
- Study level
- Honours
- Faculty
- Faculty of Business and Law
- School
- School of Accountancy
Avatar customisation for diversity training in virtual reality
Avatar representation is found to be crucial for user engagement in various types of applications and user identifications with avatars. This project aims to design and develop an environment where users can customize their avatars by looking at a virtual mirror. In this project, where users will be trained in diversity awareness, it is crucial for them to feel like the character who is in the scenario. The outcome of the project will be used in experiments to test the …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Computer Science
Surface engineering for nanoelectronic devices
Ga2O3 is an emerging wide-bandgap semiconducting material that has received enormous attention in recent years. This is due to its potential application in power devices, UV detectors and military applications that are unattainable by conventional semiconductors such as silicon.The operation and performance of these type of electronic devices rely critically on the surface quality and properties of the semiconducting materials. However, the surface atomic structures and electronic structures of Ga2O3 single crystals are not yet fully understood.The principal aim of …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Chemistry and Physics
- Research centre(s)
- Centre for Materials Science
Centre for Clean Energy Technologies and Practices
Global Health and the Law
Professor Belinda Bennett is interested in talking to students who wish to undertake research on global health and the law, including the Sustainable Development Goals, legal issues related to global health governance, global public health, and health and human rights.
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Business and Law
- School
- School of Law
- Research centre(s)
-
Australian Centre for Health Law Research
Business model innovation
Business models are becoming an important focus of innovation activities of practitioners and innovation studies of academics.When organisations want to introduce new products or services or need to transform their existing products or services, a viable business model is a critical requirement for commercial success. For example, many internet services are provided for free and require providers to find alternative sources of revenue, such as advertisements or premium services.In addition, the innovation of the business model itself is often a …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Information Systems
- Research centre(s)
- Centre for Future Enterprise
Corporate Law, Innovation and the Rise of Fintech
Dr Anne Matthew is interested in talking to students wishing to undertake research in the areas of corporate law and access to finance. This research will focus on the impact of innovation and entrepreneurship in access to finance, including for example the rise and early experiences of innovators, investors and/or fundraisers with fintech platforms. Projects may take comparative, theoretical and/or empirical approaches. This topic is led by the QUT School of Law within the Consumer Policy and Regulation research group. …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Business and Law
- School
- School of Law
Contact us
If you have questions about the best options for you, the application process, your research topic, finding a supervisor or anything else, get in touch with us today.