QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 680 matching student topics
Displaying 493–504 of 680 results
Language and Literacy
Potential projects under the topic of Language and Literacy include:Enhancing critical reading beyond the classroom with migrant and refugee-background youthCritical digital literacy and communication - how digital platforms have affected and will continue to affect literacy and communication practices in educationThe affect and affordances of algorithms on online literacy practicesHow can Aboriginal and Torres Strait Islander teacher aides or support workers assist teachers with Indigenous Language learning in the classroom?
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Teacher Education and Leadership
Characterisation of melanoma cell membranes to identify novel drug targets
Cell membrane structure and function are altered during tumour development, but to date comprehensive studies on the characterisation of cell membranes of a given cancer are scarce, or are only focused on a particular property (e.g. overall charge, global lipid composition, or specific lipid). In preliminary work we compared the lipidome (i.e. the lipid profile) of a panel of cells, and found the lipid composition of model melanoma cells to be distinct from that of other cancerous and non-cancerous cells. …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Trauma-Aware Education
Potential projects in the area of Trauma-Aware Education include:The responses of schools and early childhood services to address the impacts of trauma on children and young peopleMitigating the impacts of trauma on children and young people
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Early Childhood and Inclusive Education
Inclusive Education
Potential Topics for study in the area of Inclusive Education include:Inclusive practices for primary school teachers: design-based research study investigating the inclusion of gender and sexuality diversityBeyond NAPLAN: Promoting student engagement, achievement and wellbeing through inclusive school reform.Identifying and addressing over-representation of at-risk groups in school suspension and exclusion.Investigating the prevalence of, reasons for and alternatives to informal suspension and restrictive practices in Australian schools.What can we learn from parents of students with disability about parent-school partnerships?The increasing problem of …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Early Childhood and Inclusive Education
- Research centre(s)
-
Centre for Inclusive Education
A novel molecular targeted therapy for anaplastic prostate cancer
In advanced PCa, where the cancer has spread into the bone and other organs, the emergence of treatment resistance remains inevitable. For decades the primary form of treatment in advanced PCa has been to target the production and actions of male sex hormones, androgens, the primary developmental and survival factor of prostate tissue. While these therapies result in tumour regression and cancer control, this is temporary and treatment resistance occurs, referred to as castrate resistant prostate cancer (CRPC). In the …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Development of peptides as therapeutics to treat drug-resistant metastatic melanoma
Melanoma is a very aggressive cancer due to its metastatic potential, and the third most common in Australia. Many patients with metastatic melanoma have strong side effects, do not respond, or develop resistance to current therapies, which results in low survival rate (26% in 5-years). This project aims at developing a new class of therapeutic leads to tackle drug-resistance in metastatic melanoma.Currently, the preferred first-line regimen given to patients with metastatic melanoma is immunotherapy with antibodies (i.e. ipilimumab and nivolumab), …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Understanding the genetics of melanoma susceptibility: many roads lead to DNA repair
Repair of the damage caused by mutagens such as UV and reactive oxygen species is vital to prevent cancer and premature aging and accordingly cells have developed a suite of intricate and specific DNA repair pathways. Loss or abnormal function of components of these pathways lead to cancer pre-disposition syndromes for example breast cancer in individuals carrying mutations in the BRCA1 or BRCA2 genes. Understanding the complexities of these DNA repair pathways is vital to efforts aimed at preventing or …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
An airway chip for screening viral infection mediated immune responses
Respiratory infections such as influenza, SARS-COV-2, , and MERS are increasingly prevalent. Complications and related deaths arising from these infections are often the result of a “cytokine storm”, whereby there is an over production of proinflammatory soluble factors by immune cells, which dictates symptoms severity and mortality risk [1]. Recent works showed that immunomodulatory therapy with or without antiviral agents may improve recovery outcome. However, the screening of suitable immune-modulatory and antiviral agents relies heavily on animal models which cannot …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Characterising drivers of melanoma cell heterogeneity
Tumour cell heterogeneity is linked to tumour progression through the generation of divergent cellular behaviours such as proliferation, survival, invasion and therapy resistance. Crucially, conventional and targeted therapies generally only target highly proliferative cells in tumours leading to initial tumour regression, however alternative sub-populations underpin the return of treatment refractory disease and facilitate metastatic spread. Our laboratory is focused on understanding the regulatory drivers of cellular plasticity in melanoma to better understand progression and metastatic spread of this disease and …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Creation of fibrous tissue at moving interfaces
Extracellular matrix (ECM) secreted by cells is composed of a meshwork of fibres infiltrated with proteins and/or minerals. This fibre meshwork often matures after its creation by rearranging its structure according to local mechanical clues, or by the infiltration of new molecules.In this project, the fibre meshwork will be represented by a continuous anisotropic field. You will derive evolution equations to describe fibre creation at moving cell membranes and the subsequent maturation of the meshwork.Applications of this model include the:investigation …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
- Research centre(s)
- Centre for Biomedical Technologies
Emergence of curvature-dependent growth in mathematical models of tissue invasion
The growth of biological tissues in 3D-printed scaffold pores occurs under strong geometric controls depending on the shape and size of the pores. How this control emerges from the interaction between spatial constraints and biological processes such as cell migration and cell proliferation remains largely unknown. Existing phenomenological models of tissue growth hypothesise growth laws which directly involve curvature without considering cellular mechanisms.Recently, a reaction–diffusion mathematical model of tissue growth in porous scaffolds was proposed to investigate cell-level behaviour using …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
- Research centre(s)
- Centre for Biomedical Technologies
Defining human immune responses to a healthy gut microbiome
Many human diseases are thought to involve interactions between the gut microbiome and the immune system which shape the nature and function of immunity. These interactions between host and environment are thought to be critical regulators of health and disease.In autoimmune diseases many studies have associated presence or absence of particular microbial species with diseases and some studies have shown influence of disease-related genetics on the composition of the gut microbiome. However, no studies to date have formally addressed the …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
-
Centre for Microbiome Research
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