QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 655 matching student topics
Displaying 97–108 of 655 results
Genetics of cardiovascular disease
This research project involves investigating the genetic basis of cardiovascular disease (CVD). The project will focus on the genetically unique population of Norfolk Island. The Norfolk Island Health Study has been running for 20 yrs. Over this time the cardiovascular health of the Islanders has been tracked via the collection of relevant clinical data. In addition whole genome sequence data from the study group has been collected, which will facilitate the discovery of genetic variants that influence CVD phenotypes - …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
Microfluidic chip-based tumor-immune cancer models for biomarker discovery
In-vitro profiling of tumour-immune cell interactions in proximity can provide valuable insight into patient response to new combinatorial immunotherapies that are in the pipeline and currently being tested in clinical trials. These in-vitro models allow for a more controlled and isolated environment and provide a methodical approach for generating quantifiable data characterizing the interactions between target and effector cells. Traditionally executed in well-plates, tumour-immune models have been slowly moving towards a microfluidic chip-based approach for several reasons: better control over …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Development of a microfluidic sample processing integrated robot (micro SPIN-R)
Microfluidic devices are increasingly relied upon to address the complexity of in-vitro disease models that are intended to mimic and provide insight into in-vivo processes and reactions to novel therapies and in turn, can become powerful companion diagnostic devices essential for predicting and individual patient’s reaction to a particular treatment. However, as these microfluidic devices become more and more prominent and necessary for addressing the drug screening and disease modeling needs of the industry, we have observed a lack in …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Reversing Epithelial Mesenchymal Plasticity with Eribulin to Enhance Therapy Response
Epithelial mesenchymal plasticity (EMP) is a highly regulated and powerful cellular process that is fundamental in embryonic development (1), which is hijacked by cancer cells for metastatic progression and therapy resistance in epithelial cancers (2). Eribulin is a microtubule-inhibiting cancer drug discovered in sea sponges and approved for 3rd line therapy in metastatic breast cancer, which was shown to reverse epithelial mesenchymal transition (EMT) (3).We hypothesise that eribulin’s reversal of EMT will sensitise breast cancer cells to other therapies and …
- Study level
- Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Develop microfluidic technologies for cardiovascular and cerebrovascular diseases
The sudden rupture of vulnerable atherosclerotic plaques and subsequent thrombosis formations are responsible for most acute vascular syndromes, such as myocardial infarction and stroke. Many victims who are apparently healthy die suddenly with no prior symptoms. Such deaths could be prevented through surgery or alternative medical therapy, if vulnerable plaques were identified earlier in their natural progression.To address this pressing need, we're developing simple-to-use, high-throughput and highly-informative microfluidic biochips to understand the sequences of molecular events underlying biomechanical thrombosis (mechanobiology). …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Southern ocean aerosols: Sources, sinks and impact on cloud formation and climate
Robust prediction of human-induced global warming and future climate requires more accurate climate models. Currently, aerosol-clouds interactions represent the largest source of uncertainty in our global climate models. To reduce this uncertainty, we need a better understanding of aerosol sources, chemical and physical properties, and processes impacting their growth to sizes where they can act as Cloud Condensation Nuclei (CCN) and interact with incoming solar radiation.The Southern Ocean is a region of the world where climate and weather models, including …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Earth and Atmospheric Sciences
- Research centre(s)
-
Centre for the Environment
Ecosystem responses to climate change and human impacts on sub-Antarctic islands: a context for conservation
Sub-Antarctic islands have unique ecosystems and landscapes under increasingly pressure from climate change. In many cases this is compounded by the introduction of invasive species since their discovery by humans in the 1800s.Understanding ecosystem and environmental responses to climate change and separating them from human-induced causes of change is essential for their future protection. To do this requires quantifying long-term, natural rates and variability of change, establishing the ‘baseline’ status of ecosystems and the environment prior to human arrival, and …
- Study level
- PhD
- Faculty
- Faculty of Science
- School
- School of Biology and Environmental Science
- Research centre(s)
-
Centre for the Environment
Basic aircraft collision risk modelling and visualisation
Aircraft collision risk modelling is complex yet key to ensuring safe air transport (both crewed and uncrewed aircraft). Different collision risk models are better suited to different airspace environments which means model comparison and evaluation is an important research problem. This project takes a deeper look into a specific collision risk modelling approach: gas models.
- Study level
- Honours
- Faculty
- Faculty of Engineering
- School
- School of Electrical Engineering and Robotics
- Research centre(s)
- Centre for Robotics
Local sustainable procurement to support a circular local industry in fashion and textiles
The textile industry is one of the world’s largest, with global sales in 2016 of USD 1.5 trillion. It is also one of the most polluting industries, producing 20% of global wastewater, and contributing to 10% of carbon emissions. Fashion generates large amounts of waste, and has negative social and health impacts for workers.According to the European Community Action Plan (ECAP 2019), sustainable procurement has the potential to transform the fashion and textile industry acting as a driver for local …
- Study level
- PhD
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
-
Design Lab
Road map to local circular communities: strategies, barriers, enablers.
The textile industry is one of the world’s largest, with global sales in 2016 of USD 1.5 trillion. It is also one of the most polluting industries, producing 20% of global wastewater, and contributing to 10% of carbon emissions. Fashion generates large amounts of waste, and has negative social and health impacts for workers.Circular economy would address these issues, keep clothes and textiles at their highest value and keep clothes in continuous circulation. The transformation of the sector requires a …
- Study level
- PhD
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
-
Design Lab
Designing for individuals: Leveraging advanced manufacturing for customised products
Today’s advanced manufacturing technologies offer a unique opportunity for moving away from mass production towards mass customisation in consumer products. This presents a prospect for creative practitioners to examine their role and how their expertise align with these technologies, allowing for design innovation to drive mass customisation and establishing industrial designers as a critical stakeholder within this paradigm shift in production.
- Study level
- PhD
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
Exploring the value and potential of hyperlocal gift economies
The Australian federal government has committed to achieving net-zero carbon emissions by 2050 to address and reverse the effects of climate change and transition to a circular economy. Achieving net-zero will require a shift in how we use, share and dispose of products, and our relationship to our local communities and planet.In other words, this goal will require an extraordinary shift in the way we ordinarily live. As informal practices of circularity are already happening across Australian neighbourhoods, they have …
- Study level
- PhD
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
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